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Endosomes serve as signaling platfo...
DUSP22 inhibits lung tumorigenesis ...
UHRF1P contributes to IL-17A-mediat...
Association of TRAIL receptor with ...
The phosphatase DUSP22 inhibits UBR...
Dual-specificity phosphatase 6 defi...
DUSP8 induces TGF-beta–stimulated I...
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2019-10
MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1
Cancer Research. 2019 Oct;79(19):4978-4993.
2019-07
PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency
Cell Death and Differentiation. 2019 Jul;26 (7):1221-1234.
2019-05-30
Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability
International Journal of Molecular Sciences. 2019 May 30;20(11):Article number 2668.
2019-04
MAP4K4 inhibition promotes survival of human stem cell-derived cardiomyocytes and reduces infarct size in vivo
Cell Stem Cell. 2019 Apr;24(4):579-591.e12.
2018-12
RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell
Biochimica et Biophysica Acta-Molecular Cell Research. 2018 Feb;1865(2):259-272.
2018-12
Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation
FASEB Journal. 2018 Dec;32(12):6760-6770.
2018-09-12
GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease
Science Advances. 2018 Sep 12;4(9):Article number eaat5401.
2018-09-06
RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis
International Journal of Molecular Sciences. 2018 Sep 6;19(9):Article number 2646.
2018-08-21
DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation
Proceedings of the National Academy of Sciences of the United States of America. 2018 Aug 21;115(34):E8027-E8036.
2017-11
Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration
Oncogene. 2017 Nov;36(47):6509-6517.
2017-02
Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice
Nature Microbiology. 2017 Feb;2(2):Article number 16220.
2017-01-07
MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes
Journal of Biomedical Science. 2017 Jan 7;24:Article number 4.
2016-08
Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis
Oncotarget. 2016 Aug;7(36):57593-57605.
2016-07
GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer
Oncotarget. 2016 Jul;7(27):41748-41757.
2016-07
Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase
Oncotarget. 2016 Jul;7(31):49765-49776.
2016-03-08
Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients
Oncotarget. 2016 Mar 8;7(10):10976-10989.
2016-01
MAP4K family kinases in immunity and inflammation
Advances in Immunology. 2016 Jan;129:277-314.
2016-01
TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity
Cellular Signalling. 2016 Jan;28(1):145-151.
2014-09-12
PP4 is essential for germinal center formation and class switch recombination in mice
PLoS ONE. 2014 Sep 12;9(9):Article number e107505.
2014-08-06
HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance
Nature Communications. 2014 Aug 6;5:Article number 4602.
2014-05-07
Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity
Cell and Bioscience. 2014 May 7;4:Article number 25.
2014-04-09
The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck
Nature Communications. 2014 Apr 9;5:Article number 3618.
2014-02-15
Dual-specificity Phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation
Journal of Immunology. 2014 Feb 15;192(4):1547-1557.
2014-02
The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1
Journal of Biological Chemistry. 2014 Feb 14;289(7):4009-4017.
2013-10
Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis
Arthritis and Rheumatism. 2013 Oct;65(10):2573-2582.
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