國家衛生研究院 NHRI:Item 3990099045/7212
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    题名: The impacts of serum uric acid on arterial hemodynamics and cardiovascular risks
    作者: Hsu, PF;Chuang, SY;Yu, WC;Leu, HB;Chan, WL;Chen, CH
    贡献者: Division of Health Services and Preventive Medicine
    摘要: Hyperuricemia, and its clinical manifestation gout, is a metabolic disease process that has been recognized since the dawn of medical inquiry. Uric acid was hypothesized to be a mediator of cardiovascular disease for period of time. Epidemiological correlations of hyperuricemia with hypertension and cardiovascular events were evident for two centuries' studies. With recent animal studies shedding light on the causal mechanisms of hypertension, and clinical trials suggesting that urate-lowering therapy can lower blood pressure, there appears to be growing evidence of a connection between hyperuricemia and cardiovascular disease. To help bring this recent uric acid research into context, we have undertaken this narrative review of hyperuricemia, hypertension, its hemodynamics and its outcomes, and the risk for cardiovascular diseases.
    日期: 2013-03
    關聯: Acta Cardiologica Sinica. 2013 Mar;29(2):142-150.
    Link to: http://www.tsoc.org.tw/upload/journal/1/20130322/5.pdf
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1011-6842&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000316304100005
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84878323021
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