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Institute of Biotechnology and Pharmaceutical Research
Teng-Kuang Yeh
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DBPR116, a prodrug of BPRMU191, in ...
Discovery of a mu-opioid receptor m...
Development of a humanized antibody...
Discovery of dual MER/AXL kinase in...
Discovery of a long half-life AURKA...
A dual nociceptin and mu opioid rec...
Discovery of tetrasubstituted thiop...
Development of furanopyrimidine-bas...
2,6-Difluorobenzamide derivatives a...
Protective effect of CXCR4 antagoni...
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Showing items 21-30 of 120. (12 Page(s) Totally)
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Date
Title
Relation
2021-08-01
DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity
Life Sciences. 2021 Aug 1;278:Article number 119574.
2021-05-19
Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins
Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2021-03-30
A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment
Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 30;118(13):Article number e2015433118.
2021-01
Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors
Chemical Biology and Drug Design. 2021 Jan;97(1):51-66.
2021-01
BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy
Translational Oncology. 2021 Jan;14(1):Article number 100897.
2021-01
Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease
European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938.
2020-08
Artificial intelligence approach fighting COVID-19 with repurposing drugs
Biomedical Journal. 2020 Aug;43(4):355-362.
2020-08
Repurposing old drugs as antiviral agents for coronaviruses
Biomedical Journal. 2020 Aug;43(4):368-374.
2020-05
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors
Bioorganic Chemistry. 2020 May;98:Article number 103689.
2020-04
BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine
Neuropharmacology. 2020 Apr;166:Article number 107678.
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