國家衛生研究院 NHRI:Item 3990099045/7526

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Title:	Hematopathologic discrepancies between referral and review diagnoses: A gap between general pathologists and hematopathologists
Authors:	Chang, C;Huang, SW;Su, IJ;Chang, KC
Contributors:	Division of Infectious Diseases
Abstract:	The World Health Organization (WHO) lymphoma classification has been widely adopted by hematopathologists. However, its practical application by general pathologists is largely unknown. Using a hematopathology consultation program in Taiwan, we reviewed 406 cases. Diagnostic discrepancies were scored based upon whether the divergence would alter disease management according to National Comprehensive Cancer Network guidelines. Major discrepancies accounted for 55% (222/406), minor discrepancies for 5% (20/406) and agreement for 40% (164/406) cases. The more common groups in major discrepancies were non-diagnostic/ambiguous referral reports (116/222, 52%), tumor type revisions (52/222, 23%) and changes from malignant to benign lesions (32/222, 14%). In a total of 259 cases of lymphoma, the concordance rates were 41% (77/187) and 33% (24/72) for B-cell and T/natural killer (NK)-cell lymphomas, respectively. It appears that the WHO approach has made lymphoma classification rather poorly reproducible at least in countries where extensive use of an ancillary technique is not employed by general pathologists.
Date:	2014-05
Relation:	Leukemia & Lymphoma. 2014 May;55(5):1023-1030.
Link to:	http://dx.doi.org/10.3109/10428194.2013.831849
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1042-8194&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000335217100011
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84899754556
Appears in Collections:	[Ih-Jen Su(2002-2015)] Periodical Articles

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