國家衛生研究院 NHRI:Item 3990099045/7576
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    题名: The impact of sarcopenic obesity on physical performance in elderly from START preliminary result
    作者: Chang, CI;Huang, KC;Chan, DC;Wu, CH;Lin, CC;Chen, CY;Hsiung, CA;Hsu, CC;Chen, CY
    贡献者: Division of Geriatric Research;Division of Biostatistics and Bioinformatics
    摘要: Objective: During aging process, a series of modifications such as increased fat percentage with decreased skeletal muscle mass occurred owing to the change of endocrine and metabolic system. The impact of sarcopenic (low skeletal muscle mass) obesity (high fat percentage) on physical performance will be verified.Methods: Total 2,629 subjects aged 65 and over were recruited from Sarcopenia and Translational Aging Research in Taiwan (START) including several studies from north, middle, and south part of Taiwan. Eligible subjects were measured body composition by bio-impedance analysis with Tanita BC-418 machine. Additionally, physical performance including handgrip strength (kg), gait speed (m/sec), short physical performance battery, and timed up and go test (sec) were performed and collected from each study. Demographic information and fall event during the past one year were recorded concurrently. In order to establish the norm of skeletal muscle mass and fat percentage, almost 1000 young adults (half in each gender) aged 20-40 were recruited for body composition with the same device. Results: Previous result showed that the definition of low skeletal muscle mass set at 2 standard deviation (SD) below the mean value of appendicular skeletal muscle index (ASMI) in the young reference groups as 6.76 and 5.28 kg/m2, respectively. The prevalence of sarcopenia in the total pooled elderly population read 11.3% for male and 8.1% for female. Based on the mean of fat percentage of young health adults, cut-off point at 2 SD over mean was 31.41% for male and 39.17% for female. The prevalence of obesity for age over years old in START was around 1% and 2%, respectively. Subjects were classified in 4 groups, i.e. (1) normal, (2) sarcopenia only, (3) obesity only, and (4) sarcopenic obesity, according to the ASMI and fat percentage. Group 2 and 4 were older but group 3 had more chronic disease numbers compared with the other groups. The mean of hand grip strength was smaller in group 2, 3, and 4 than group 1 and group 4 was the weakest. The patterns of the other physical performance, including gait speed, timed up and go test, and fall experience were similar among these groups. After covariates adjusted, sarcopenia only and obesity only was worse than normal group in physical performance and sarcopenic obesity group was the worst. Conclusions: In comparison of various physical performances, either sarcopenia or obesity of the elderly was worse than normal group. In addition, the impact of sarcopenia and obesity has synergistic effect on all physical performance in the elderly.
    日期: 2013-10
    關聯: 2013年公衛聯合年會. 2013 Oct:73.
    Link to: http://www.publichealth.org.tw/upload/files/2013TPHAAnnual.pdf
    显示于类别:[許志成] 會議論文/會議摘要
    [陳慶餘(2006-2010)] 會議論文/會議摘要
    [熊昭] 會議論文/會議摘要
    [黃國晉] 會議論文/會議摘要

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