國家衛生研究院 NHRI:Item 3990099045/7649
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 864277      在线人数 : 451
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/7649


    题名: Association between recent use of fluoroquinolones and rhegmatogenous retinal detachment: A population-based cohort study
    作者: Kuo, SC;Chen, YT;Lee, YT;Fan, NW;Chen, SJ;Li, SY;Liu, CJ;Chen, TL;Chen, TJ;Fung, CP
    贡献者: Division of Infectious Diseases
    摘要: Background: An association between use of oral fluoroquinolones (FQs) and retinal detachment remains controversial. This study was to determine the association of recent use of oral FQs and rhegmatogenous retinal detachment (RRD) after adjustment for confounding factors known to be associated with RRD.Methods:This retrospective population-based cohort study with parallel groups included adults treated with an oral FQ (FQ cohort 178 179 prescriptions) and propensity-score–matched adults treated with oral amoxicillin (amoxicillin cohort 178 179 prescriptions). The data were extracted from the Taiwan National Health Insurance Research Database from 1998 to 2010. Interaction terms were used to identify populations at risk. RRD was defined according to the International Classification of Disease, ninth revision.Results:During the 90-day follow-up period, 96 patients (0.054%) in the FQ cohort developed RRD compared to 46 (0.026%) among the matched amoxicillin cohort. The overall adjusted hazard ratio (aHR) for FQ use and RRD was 2.07 (95% confidence interval [CI], 1.45-2.96). The interval between use of oral FQs and onset of RRD was 35.5 days (interquartile range, 14-57). Interaction terms were not significant for age, sex, diabetes, indications for antimicrobials and underlying ophthalmic conditions. The aHRs differed for specific FQs. These were ciprofloxacin 10.68 (95% CI, 3.28-34.82), levofloxacin 2.41 (0.76-7.68), norfloxacin 2.00 (1.06-3.79), and ofloxacin 1.17 (0.59-2.31).Conclusions:The use of oral FQs was associated with the subsequent occurrence of RRD. The FQ risk was independent of age, sex, diabetes, indications for antimicrobials, or underlying ophthalmic conditions. Certain FQs carried higher risk of RRD.
    日期: 2014-01
    關聯: Clinical Infectious Diseases. 2014 Jan;58(2):197-203.
    Link to: http://dx.doi.org/10.1093/cid/cit708
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1058-4838&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000329131300011
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84891792341
    显示于类别:[郭書辰] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    PB2013112601.pdf236KbAdobe PDF456检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈