國家衛生研究院 NHRI:Item 3990099045/7779
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/7779


    Title: A recombinant PPRE-driven luciferase bioassay for identification of potential PPAR agonists
    Authors: Tsai, FY;Cheng, YT;Tsou, TC
    Contributors: Division of Environmental Health and Occupational Medicine
    Abstract: A recombinant Huh7-PPRE-Luc cell line, carrying a peroxisome proliferator response element (PPRE)-driven luciferase gene, is an efficient tool for evaluation of potential peroxisome proliferator-activated receptor (PPAR) agonists. The cells exhibited a good dose–response induction in PPRE-driven luciferase activity by three subtypes of PPAR agonists as well as by a retinoid X receptor agonist, 9-cis-retinoic acid. Here, the bioassay is fitted into a 96-well plate format for high-throughput screening purpose.
    Date: 2014-01
    Relation: Vitamins and Hormones. 2014 Jan;94:427-435.
    Link to: http://dx.doi.org/10.1016/B978-0-12-800095-3.00015-8
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000331015200015
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84891394817
    Appears in Collections:[Tsui-Chun Tsou] Books/Book Section

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