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Institute of Biotechnology and Pharmaceutical Research
Ming-Shiu Hung
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Showing items 11-20 of 31. (4 Page(s) Totally)
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Date
Title
Relation
2018-08-21
DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation
Proceedings of the National Academy of Sciences of the United States of America. 2018 Aug 21;115(34):E8027-E8036.
2018-04
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy
Bioorganic Chemistry. 2018 Apr;77:600-607.
2017-11
Caveolin-1 secreted from adipose tissues and adipocytes functions as an adipogenesis enhancer
Obesity. 2017 Nov;25(11):1932-1940.
2016-07-22
Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons
Nature Communications. 2016 Jul 22;7:Article number 12199.
2016-01
Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1
Journal of Medicinal Chemistry. 2016 Jan;59 (1):282-293.
2016-01
Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy
Journal of Medicinal Chemistry. 2016 Jan;59(1):419-430.
2015-10
Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening
Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819.
2015-05
A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis
Diabetes, Obesity and Metabolism. 2015 May;17(5):495-504.
2014-08
Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors
Bioorganic and Medicinal Chemistry Letters. 2014 Aug;24(15):3403-3406.
2013-11-13
Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice
Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933.
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