國家衛生研究院 NHRI:Item 3990099045/8226
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    题名: Identification of the first imported KPC-3 Klebsiella pneumoniae from the USA to Taiwan
    作者: Tang, HJ;Chen, YT;Chiang, T;Fung, CP;Chuang, YC;Kristopher Siu, L
    贡献者: Institute of Molecular and Genomic Medicine;Division of Infectious Diseases
    摘要: Establishment of KPC-associated genes into a new region usually requires travellers with hospital admission and their carriage into the communities. In this report, a worldwide spreading clone carrying KPC-3 was isolated from the sputum of a hospitalised patient with a serious infection who had just come from the USA and had been admitted to a New York hospital. By genetic comparison with a strain isolated from New Jersey (NJ-KPC-21), this isolate from the traveller was genetically related. The blaKPC-3 gene was harboured on a large plasmid with a complex structure of a Tn3-based transposon, Tn4401a. The KPC-3-carrying plasmid was very similar (>99.9% identity) to the 113 637-bp blaKPC-3-encoding plasmid pKpQIL that originated from the 2006 epidemic carbapenem-resistant Klebsiella pneumoniae outbreak in Israel. With the first recognition of KPC-2 in 2011 and continuing spread, physicians should be aware of the coming of KPC-3 K. pneumoniae in Taiwan.
    日期: 2014-11
    關聯: International Journal of Antimicrobial Agents. 2014 Nov;44(5):431-435.
    Link to: http://dx.doi.org/10.1016/j.ijantimicag.2014.07.009
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0924-8579&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000344938800009
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84908394470
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