Nanoparticle-based formulation, composed of organic, inorganic or organic/inorganic hybrid materials, have been demonstrated for their promising applications in clinical diagnosis and therapeutics purposes. In this presentation, two types of nanoparticles, one organic and the other inorganic type of nanoparticles, will be introduced and reported. The ? rst example is the PLGA nanoparticles (200 – 400 nm) that are loaded with neurotrophic factors or Chondrointinase ABC for implanting into rat spinal cord injury to treat contusive spinal cord injury. The other example is the radioactive gold nanoparticles (10 – 30 nm) that are placed into the rat brain to treat brain tumor. The radioactive gold nanoparticles are produced from neutron activation, and can emit beta particles and gamma ray for both therapeutic and imaging purposes.
Date:
2014-08
Relation:
Journal of Neurochemistry. 2014 Aug;130(Suppl. s1):23.
