國家衛生研究院 NHRI:Item 3990099045/8465
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/8465


    Title: Change of suicidality among heroin users: 1 month after methadone maintenance treatment
    Authors: Wang, SC;Huang, CL;Wang, NY;Chan, CH;Liu, YL;Chen, CY;Ho, IK
    Contributors: Center for Neuropsychiatric Research
    Abstract: Aims: Suicide is a leading cause of death among heroin users. Factors affecting suicidality during treatment remain unclear. This study aimed to investigate the heroin users’ suicidality before and after 1 month of methadone maintenance treatment (MMT). Factors associated with change in suicidality were also explored.Methods: A total of 597 newly admitted MMT patients were recruited from 8 hospitals located in the northern and mid-Taiwan. Demographics, and history of substance abuse and treatment were obtained from medical records. Suicidality was assessed by research nurses using suicidality module of Mini International Neuropsychiatric Interview (MINI). After the first month of MMT, subjects retained in treatment were re-assessed for their suicidality. Logistic regression analyses were used to determine the factors linked to change in suicidality during the first month of MMT.Results: Among the 389 patients with suicidality reassessment, 83 (21.3%) improved, and 58 (14.9%) worsened or had no improvement for their suicide risk. Contrast to the 248 subjects with no suicidality during the past 1 month of MMT, those with no improvement were significantly associated with no full-time job (e.g., part-time job: OR = 6.0, p < 0.001; unemployed: OR = 7.5, p < 0.001), financial difficulty (e.g., loan from others: OR = 2.6, p < 0.01; social welfare support: OR = 13.0, p < 0.01), HIV-infected (OR = 2.8, p < 0.01), and recent use of methamphetamine (OR = 1.1, p < 0.01). On the other hand, the improving group was significantly associated with HIV-infected (OR = 2.1, p < 0.05), and use of antidepressant before MMT (OR = 3.3, p < 0.01) relative to those with no suicidality during the past month.Conclusions: The MMT will help heroin users to reduce suicide risk. However, service providers should pay attention to those with problems of unemployment, financial difficulty and concomitant use of other illicit drugs.
    Date: 2015-01
    Relation: Drug and Alcohol Dependence. 2015 Jan;146:e17.
    Link to: http://dx.doi.org/10.1016/j.drugalcdep.2014.09.726
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0376-8716&DestApp=IC2JCR
    Appears in Collections:[Yu-Li Liu] Conference Papers/Meeting Abstract
    [Sheng-Chang Wang] Conference Papers/Meeting Abstract

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