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Discovery of a long half-life AURKA...
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2024-06-01
Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus
Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
2023-11-15
Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors
Bioorganic and Medicinal Chemistry. 2023 Nov 15;95:Article number 117502.
2023-07-18
Marine diterpenoid targets STING palmitoylation in mammalian cells
Communications Chemistry. 2023 Jul 18;6:Article number 153.
2022-08
AKT phosphorylation as a predictive biomarker for PI3K/mTOR dual inhibition-induced proteolytic cleavage of mTOR companion proteins in small cell lung cancer
Cell and Bioscience. 2022 Aug;12:Article number 122.
2022-01-04
Deformation of the nucleus by TGF beta 1 via the remodeling of nuclear envelope and histone isoforms
Epigenetics and Chromatin. 2022 Jan 04;15:Article number 1.
2021-06-02
Development of a respiratory syncytial virus vaccine using human hepatitis B core-based virus-like particles to induce mucosal immunity
Vaccine. 2021 Jun 2;39(24):3259-3269.
2021-05-19
Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins
Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2021-03-08
The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal
Scientific Reports. 2021 Mar 8;11:Article number 5358.
2020-11-28
Exercise and the Cisd2 prolongevity gene: Two promising strategies to delay the aging of skeletal muscle
International Journal of Molecular Sciences. 2020 Nov 28;21(23):Article number 9059.
2020-08-19
Lamin A-mediated nuclear lamina integrity is required for proper ciliogenesis
EMBO Reports. 2020 Oct 05;21(10):Article number e49680.
2019-12
Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis
Aging Cell. 2019 Dec;Article number e13090.
2019-08-15
Sun1 mediates interkinetic nuclear migration and Notch signaling in the neurogenesis of zebrafish
Stem Cells and Development. 2019 Aug 15;28(16):1116-1127.
2019-03-01
Interference of DNAJB6/MRJ isoform switch by morpholino inhibits replication of HIV-1 and RSV
Molecular Therapy. Nucleic Acids. 2019 Mar 1;14:251-261.
2018-05-10
Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition
European Journal of Medicinal Chemistry. 2018 May 10;151:533-545.
2017-09
Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture
Journal of Cell Biology. 2017 Sep;216(9):2827-2841.
2017-09
Adaptation of influenza A (H7N9) virus in primary human airway epithelial cells
Scientific Reports. 2017 Sep;7:Article number 11300.
2017-08-07
Utrophin compensates dystrophin loss during mouse spermatogenesis
Scientific Reports. 2017 Aug 7;7:Article number 7372.
2017-04-05
In vivo inhibition of influenza A virus replication by RNA interference targeting the PB2 subunit via intratracheal delivery
PLoS ONE. 2017 Apr 5;12(4):Article number e0174523.
2015-08
Sun1 deficiency leads to cerebellar ataxia in mice
Disease Models and Mechanisms. 2015 Aug;8(8):957-967.
2014-12
Large isoform of mammalian relative of dnaJ is a major determinant of human susceptibility to HIV-1 infection
EBioMedicine. 2014 Dec;1(2-3):126-132.
2004-03-01
A reporter-based assay for identifying hepatitis C virus inhibitors based on subgenornic replicon cells
Journal of Virological Methods. 2004 Mar;116(1):27-33.
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