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http://ir.nhri.org.tw/handle/3990099045/8530
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| Title: | ABO blood types and cancer risk-A cohort study of 339,432 subjects in Taiwan |
| Authors: | Sun, W;Wen, CP;Lin, J;Wen, C;Pu, X;Huang, M;Tsai, MK;Tsao, CK;Wu, X;Chow, WH |
| Contributors: | Division of Health Services and Preventive Medicine |
| Abstract: | BACKGROUND: The associations of laboratory-based ABO phenotypes with cancer risks and mortality have not been systematically determined. METHODS: The study subjects were 339,432 healthy individuals with laboratory-based blood types from a Taiwan cohort. RESULTS: Compared to blood type O, blood type A was significantly associated with an elevated risk of stomach cancer incidence (Hazard Ratio [HR], 1.38 [95% CI, 1.11-1.72]) and mortality (HR, 1.38 [95% CI, 1.02-1.86]) compared with blood type O, after adjusting for age, sex, education, smoking, alcohol drinking, physical activity, and body mass index. Non-O blood types were associated with an elevated risk of pancreatic cancer, with blood type B reaching statistical significance for incidence (HR, 1.59 [95% CI, 1.02-2.48]) and mortality (HR, 1.63 [95% CI, 1.02-2.60]). In contrast, kidney cancer risk was inversely associated with blood type AB (HR, 0.41 [95% CI, 0.18-0.93]) compared to type O. CONCLUSION: Cancer risks vary in people with different ABO blood types, with elevated risks of stomach cancer associated with blood type A and pancreatic cancer associated with non-O blood types (A, B, and AB). |
| Date: | 2015-04 |
| Relation: | Cancer Epidemiology. 2015 Apr;39(2):150-156. |
| Link to: | http://dx.doi.org/10.1016/j.canep.2014.12.006 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1877-7821&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:000351233200003 |
| Cited Times(Scopus): | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84926204395 |
| Appears in Collections: | [溫啟邦(2001-2010)] 期刊論文
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| PUB25600007.pdf | | 305Kb | Adobe PDF | 412 | View/Open |
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