國家衛生研究院 NHRI:Item 3990099045/8661
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/8661


    Title: Tailoring highly branched poly([small beta]-amino ester)s: A synthetic platform for epidermal gene therapy
    Other Titles: Tailoring highly branched poly(β-amino ester)s: A synthetic platform for epidermal gene therapy
    Authors: Huang, JY;Gao, Y;Cutlar, L;O'Keeffe-Ahern, J;Zhao, T;Lin, FH;Zhou, D;McMahon, S;Greiser, U;Wang, W;Wang, W
    Contributors: Institute of Biomedical Engineering and Nanomedicine
    Abstract: Highly branched poly(beta-amino ester)s (HPAEs) were designed and synthesised for safe and efficient gene delivery to human keratinocytes. HPAEs outperformed commercial transfection reagents: PEI and SuperFect[registered sign], for both transfection efficiency and biocompatibility. A 22 and 3.4 fold enhancement of gene transfection was seen coupled with superior biocompatibility.
    Date: 2015-05
    Relation: Chemical Communications. 2015 May;51(40):8473-8476.
    Link to: http://dx.doi.org/10.1039/C5CC02193F
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1359-7345&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000354043200019
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84928978337
    Appears in Collections:[Feng-Huei Lin] Periodical Articles

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