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生技與藥物研究所
伍素瑩
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顯示項目26-46 / 46. (共2頁)
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題名
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2010-03-11
5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors
Journal of Medicinal Chemistry. 2010 Mar 11;53(5):2309-2313.
2010-02-01
Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor
ChemMedChem. 2010 Feb 1;5(2):255-267.
2009-10
(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases
Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055.
2009-08-13
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach
Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945.
2009-07-23
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity
Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233.
2009-06
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]
European Journal of Medicinal Chemistry. 2009 Jun;44(6):2763-2763.
2009-04-23
Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists
Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622.
2009-02-26
Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity
Journal of Medicinal Chemistry. 2009 Feb 26;52(4):1050-1062.
2008-12-25
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents
Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167.
2008-08
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors
European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.
2008-03-01
Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold
Bioorganic and Medicinal Chemistry Letters. 2008 Mar;18(5):1623-1627.
2008
Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases
Journal of Biomedicine and Biotechnology. 2008; 2008:Article number 841312.
2006-10-19
Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
Journal of Medicinal Chemistry. 2006 Oct;49(21):6421-6424.
2006-08-24
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease
Journal of Medicinal Chemistry. 2006 Aug;49(17):5154-5161.
2006-06-15
Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies
Journal of Medicinal Chemistry. 2006 Jun;49(12):3485-3495.
2006-05-04
Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities
Journal of Medicinal Chemistry. 2006 May;49(9):2703-2712.
2006-02-09
Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies
Journal of Medicinal Chemistry. 2006 Feb;49(3):1212-1216.
2006-01-12
2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380.
2005-12-29
Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities
Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208.
2005-12-15
The effect of N-terminal truncation on double-dimer assembly of goose delta-crystallin
Biochemical Journal. 2005 Dec;392(Pt. 3):545-554.
2005-07-01
Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors
Bioorganic and Medicinal Chemistry Letters. 2005 Jul;15(13):3271-3275.
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