本發明係關於一種奈米藥物遞送系統,藉由小於一微米(10-6meter)的紅血球微囊(Red blood cell-derived vesicles)將外來物質封裝並傳遞進入細胞中。該外來物質可為至少一種選自螢光機團、核酸、超順磁性化合物及治療劑者。其中紅血球微囊能夠將封裝物質傳送進入包括幹細胞等細胞中。經遞送於細胞或幹細胞中遞物質可使用適當的儀器在活體內或活體外進行追蹤。Red blood cell-derived vesicles (RDV) are a nanoparticle drug delivery system. The RDV are smaller than one micrometer, capable of encapsulating and delivering an exogenous substance into cells. The substance may be at least one selected from the group consisting of fluorophores, nucleic acids, superparamagnetic compounds and therapeutic agents. The RDV are capable of delivering encapsulated substances into cells including stem cells. The delivered substance within the cell or stem cell may be traced or tracked using a suitable device either in vitro or in vivo.