本發明是關於一種調節細胞循環以及利用一種過氧化體增殖劑活化受體γ興奮劑與一種甲羥戊酸生物合成路徑抑制劑,或是一種甲羥戊酸拮抗劑來治療癌症之醫藥組成物。This invention relates to a method of regulating the cell cycle and treating cancer with a peroxisome proliferator-activated receptor γ agonist and a mevalonate pathway inhibitor or a mevalonate antagonist.