國家衛生研究院 NHRI:Item 3990099045/9115
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    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/9115


    题名: 一種抗病毒之醫藥組合物
    其它题名: Anti-virus compounds
    作者: Hsu, TA;Hsieh, HP;Juan, LJ;Chang, SY;Kuo, YH
    贡献者: Institute of Biotechnology and Pharmaceutical Research;National Institute of Cancer Research
    摘要: 本發明係有關於一種用於抑制受到皰疹病毒屬感染的醫藥組成物,係具有如式(I)結構之化合物。其中R1及 R2分別為R或C(O)R;或R1及R2共同連結為(亞甲基)m; R3、R4及R5分別為R, OR, C(O)R,或OC(O)R;或R3,R4及R5中的任意2個共同連結為O(CH2)nO;Ar為芳香烴; Z1與Z2分別為亞甲基或C(O);R6與R7分別為R, OR, SR,或NRR’;或R6與R7共同連結為氧,硫或NR;其中R與 R’分別為氫,烷基,(亞甲基)o-芳香烴,(亞甲基)p-雜芳香烴,環基,是雜環基;m及n分別代表1,2,3或4;o及p分別代表0,1,2,3,4,5或6。This invention features a medical composition for treating infection by herpesvirus. The composition includes an arylnaphthalene compound of formula (I). Each of R1 and R2, independently is R or C(O)R; or R1 and R2 taken together is (CH2)m; each of R3, R4, and R5, independently, is R, OR, C(O)R, or OC(O)R; or any two of R3, R4, and R5 taken together is O(CH2)nO; Ar is aryl; each of Z1 and Z2, independently, is CH2 or C(O); and each of R6 and R7, independently, is R, OR, SR, or NRR’; or R6 and R7 taken together is O, s, or NR; in which each of R and R’, independently, is H, alkyl, (CH2)o-aryl, (CH2)p-heteroaryl, cyclyl, or heterocyclyl; each of m and n, independently, is 1, 2, 3, or 4; and each of o and p, independently, is 0, 1, 2, 3, 4, 5, or 6.
    日期: 2008-02-11
    關聯: I293248/2008-02-11
    Link to: https://twpat1.tipo.gov.tw/tipotwoc/tipotwkm?!!FR_I293248
    显示于类别:[徐祖安] 專利
    [謝興邦] 專利
    [阮麗蓉(2000-2006)] 專利

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