國家衛生研究院 NHRI:Item 3990099045/9138
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    題名: Inducible expression of gasdermin A3 in the epidermis causes epidermal hyperplasia and skin inflammation
    作者: Lin, HY;Lin, PH;Wu, SH;Yang, LT
    貢獻者: Institute of Cellular and Systems Medicine
    摘要: The epidermis forms a critical barrier to defend against environmental insults. It is maintained by epidermal keratinocytes undergoing an orchestrated program of proliferation, differentiation, and death, which could be disrupted by gene mutations and cause skin diseases. Gasdermin A (GSDMA) is expressed in epithelial cells of the upper gastrointestinal tract, lung, and skin (1, 2). GSDMA is involved in apoptosis of the gastric epithelium cells (3) and has been linked with asthma susceptibility in genetic association studies (4). The function of GSDMA in the skin remains unclear. Among three GSDMA orthologs (Gsdma1-3) in mice, Gsdma1 and Gsdma3 are expressed in the differentiating keratinocytes of the epidermis.
    日期: 2015-11
    關聯: Experimental Dermatology. 2015 Nov;24(11):897-899.
    Link to: http://dx.doi.org/10.1111/exd.12797
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0906-6705&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000365404300021
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84983167681
    顯示於類別:[楊良棟] 期刊論文

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