國家衛生研究院 NHRI:Item 3990099045/9288
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9288


    Title: Associations of body mass index, smoking, and alcohol consumption with prostate cancer mortality in the Asia cohort consortium
    Authors: Fowke, JH;McLerran, DF;Gupta, PC;He, J;Shu, XO;Ramadas, K;Tsugane, S;Inoue, M;Tamakoshi, A;Koh, WP;Nishino, Y;Tsuji, I;Ozasa, K;Yuan, JM;Tanaka, H;Ahn, YO;Chen, CJ;Sugawara, Y;Yoo, KY;Ahsan, H;Pan, WH;Pednekar, M;Gu, D;Xiang, YB;Sauvaget, C;Sawada, N;Wang, R;Kakizaki, M;Tomata, Y;Ohishi, W;Butler, LM;Oze, I;Kim, DH;You, SL;Park, SK;Parvez, F;Chuang, SY;Chen, Y;Lee, JE;Grant, E;Rolland, B;Thornquist, M;Feng, Z;Zheng, W;Boffetta, P;Sinha, R;Kang, D;Potter, JD
    Contributors: Division of Health Services and Preventive Medicine
    Abstract: Many potentially modifiable risk factors for prostate cancer are also associated with prostate cancer screening, which may induce a bias in epidemiologic studies. We investigated the associations of body mass index (weight (kg)/height (m)2), smoking, and alcohol consumption with risk of fatal prostate cancer in Asian countries where prostate cancer screening is not widely utilized. Analysis included 18 prospective cohort studies conducted during 1963-2006 across 6 countries in southern and eastern Asia that are part of the Asia Cohort Consortium. Body mass index, smoking, and alcohol intake were determined by questionnaire at baseline, and cause of death was ascertained through death certificates. Analysis included 522,736 men aged 54 years, on average, at baseline. During 4.8 million person-years of follow-up, there were 634 prostate cancer deaths (367 prostate cancer deaths across the 11 cohorts with alcohol data). In Cox proportional hazards analyses of all cohorts in the Asia Cohort Consortium, prostate cancer mortality was not significantly associated with obesity (body mass index >25: hazard ratio (HR) = 1.08, 95% confidence interval (CI): 0.85, 1.36), ever smoking (HR = 1.00, 95% CI: 0.84, 1.21), or heavy alcohol intake (HR = 1.00, 95% CI: 0.74, 1.35). Differences in prostate cancer screening and detection probably contribute to differences in the association of obesity, smoking, or alcohol intake with prostate cancer risk and mortality between Asian and Western populations and thus require further investigation.
    Date: 2015-09
    Relation: American Journal of Epidemiology. 2015 Sep;182(5):381-389.
    Link to: http://dx.doi.org/10.1093/aje/kwv089
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0002-9262&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000361388700002
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84941656073
    Appears in Collections:[Wen-Harn Pan] Periodical Articles
    [Shao-Yuan Chuang] Periodical Articles

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