| 2013-06 |
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867. |
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| 2013-05 |
Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus |
Antiviral Research. 2013 May;98(2):228-241. |
|
| 2013-05 |
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules |
Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787. |
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| 2013-05 |
Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors |
Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903. |
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| 2013-02 |
Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems |
Antimicrobial Agents and Chemotherapy. 2013 Feb; 57(2):723-733. |
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| 2013-01 |
3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor |
ChemMedChem. 2013 Jan;8(1):136-148. |
|
| 2012-12-13 |
Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity |
Journal of Medicinal Chemistry. 2012 Dec 13;55(23):10363-10377. |
|
| 2012-12 |
An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold |
Journal of the Chinese Chemical Society. 2012 Dec;59(12):1548-1554. |
|
| 2012-09 |
Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization |
ChemMedChem. 2012 Sep;7(9):1546-1550. |
|
| 2012-09 |
Putative tumor metastasis-associated genes in human gastric cancer |
International Journal of Oncology. 2012 Sep;41(3):1068-1084. |
|
| 2012-07 |
Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors |
International Journal of Obesity. 2012 Jul;36(7):999-1006. |
|
| 2012-06-07 |
3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659. |
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| 2012-06 |
EGFR and myosin II inhibitors cooperate to suppress EGFR-T790M-mutant NSCLC cells |
Molecular Oncology. 2012 Jun;6(3):299-310. |
|
| 2012-02 |
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents |
Investigational New Drugs. 2012 Feb;30(1):164-175. |
|
| 2012-02 |
Discovery of novel stem cell mobilizers that target the CXCR4 receptor |
ChemMedChem. 2012 Feb;7(2):209-212. |
|
| 2012-01 |
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor |
Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53. |
|
| 2012-01 |
BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML |
British Journal of Cancer. 2012 Jan;106(3):475-481. |
|
| 2012-01 |
A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors |
Anticancer Research. 2012 Jan;32(1):147-151. |
|
| 2011-11 |
Isolation and biological activities of phenanthroindolizidine and septicine alkaloids from the formosan tylophora ovata |
Planta Medica. 2011 Nov;77(17):1932-1938. |
|
| 2011-09 |
Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway |
Journal of Virology. 2011 Sep;85(17):9114-9126 |
|
| 2011-07-25 |
The first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside |
Chemistry-A European Journal. 2011 Jul 25;17(31):8696-8703. |
|
| 2011-07 |
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 . |
|
| 2011-06 |
Hot topic: Opportunities and potential challenges for the treatment of metabolic syndrome |
Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1420. |
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| 2011-04 |
Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2011 Apr;21(7):1948-1952. |
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| 2011-03 |
Successful propagation of flavivirus infectious cDNAs by a novel method to reduce the cryptic bacterial promoter activity of virus genomes |
Journal of Virology. 2011 Mar;85(6):2927-2941. |
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