國家衛生研究院 NHRI:
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    日期題名關聯
    2014-01-08 Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer PLoS ONE. 2014 Jan 8;9(1):Article number e83160.
    2013-11-13 Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933.
    2013-11 BPR0C305, an orally active microtubule-disrupting anticancer agent Anticancer Drugs. 2013 Nov;24(10):1047-1057.
    2013-06-28 Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260.
    2013-06 c-Jun-mediated anti-cancer mechanisms of tylophorine Carcinogenesis. 2013 Jun;34(6):1304-1314.
    2013-06 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867.
    2013-05 Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus Antiviral Research. 2013 May;98(2):228-241.
    2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787.
    2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903.
    2013-02 Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems Antimicrobial Agents and Chemotherapy. 2013 Feb; 57(2):723-733.

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