國家衛生研究院 NHRI:
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    近3年内发表的文件:1(0.91%)
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    最后更新时间: 2024-11-28 17:49


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    显示项目1-10 / 110. (共11页)
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    日期题名關聯
    2022-11 Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
    2021-08-01 DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity Life Sciences. 2021 Aug 1;278:Article number 119574.
    2021-01 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy Translational Oncology. 2021 Jan;14(1):Article number 100897.
    2019-04-01 A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
    2019-04-01 The in vivo antinociceptive and mu-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone European Journal of Medicinal Chemistry. 2019 Apr 1;167:312-323.
    2019-03 Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors Bioorganic Chemistry. 2019 Mar;83:520-525.
    2018-04 4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy Bioorganic Chemistry. 2018 Apr;77:600-607.
    2018-01-01 Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 European Journal of Medicinal Chemistry. 2018 Jan 1;143:611-620.
    2017-06-22 Targeting coronaviral replication and cellular JAK2 mediated dominant NF-kappaB activation for comprehensive and ultimate inhibition of coronaviral activity Scientific Reports. 2017 Jun 22;7:Article number 4105.
    2017-01 A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247.

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