國家衛生研究院 NHRI:Item 3990099045/9541
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    题名: Cocktail drug delivery chip for cancer drug screening
    作者: Chen, YT;Wu, RG;Yang, CS;Tseng, FG
    贡献者: Institute of Biomedical Engineering and Nanomedicine
    摘要: This study introduces a combinatory assay platform that allows high-throughput but low-drug-dosage screening of five anti-cancer drugs as a cocktail for personalized cancer treatment. Photosensitive PEGDA hydrogel was employed for drug dosage definition through drop array formation and selective UV crosslinking process. The finally defined cocktail drugs in hydrogel will be directly released in parallel when combined with cell chips. This device is capable to combine 5 drugs with 1000 folds dynamic range in 30 second with low drug consumption for in-parallel cocktail screening process.
    日期: 2015-06
    關聯: 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems(TRANSDUCERS). 2015 Jun:735-738.
    Link to: http://dx.doi.org/10.1109/TRANSDUCERS.2015.7181028
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000380461400183
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84955455281
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