國家衛生研究院 NHRI:Item 3990099045/9585
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 925256      線上人數 : 858
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/9585


    題名: Cellular immune activity biomarker neopterin is associated hyperlipidemia: Results from a large population-based study
    作者: Chuang, SC;Boeing, H;Vollset, SE;Midttun, O;Ueland, PM;Bueno-de-Mesquita, B;Lajous, M;Fagherazzi, G;Boutron-Ruault, MC;Kaaks, R;Kuehn, T;Pischon, T;Drogan, D;Tjonneland, A;Overvad, K;Quiros, JR;Agudo, A;Molina-Montes, E;Dorronsoro, M;Huerta, JM;Barricarte, A;Khaw, KT;Wareham, NJ;Travis, RC;Trichopoulou, A;Lagiou, P;Trichopoulos, D;Masala, G;Agnoli, C;Tumino, R;Mattiello, A;Peeters, PH;Weiderpass, E;Palmqvist, R;Ljuslinder, I;Gunter, M;Lu, Y;Cross, AJ;Riboli, E;Vineis, P;Aleksandrova, K
    貢獻者: Division of Health Policy Translation
    摘要: BACKGROUND: Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). Measurements of waist circumference, triglycerides, high-density lipoprotein cholesterol (HDLC), systolic and diastolic blood pressure, glycated hemoglobin as components of MetS definition, and plasma total neopterin concentrations were performed in 594 participants recruited in the European Prospective Investigation into Cancer and Nutrition (EPIC). RESULTS: Higher total neopterin concentrations were associated with reduced HDLC (9.7 %, p < 0.01 for men and 9.2 %, p < 0.01 for women), whereas no association was observed with the rest of the MetS components as well as with MetS overall (per 10 nmol/L: OR = 1.42, 95 % CI = 0.85-2.39 for men and OR = 1.38, 95 % CI = 0.79-2.43). CONCLUSIONS: These data suggest that high total neopterin concentrations are cross-sectionally associated with reduced HDLC, but not with overall MetS.
    日期: 2016-02-25
    關聯: Immunity and Ageing. 2016 Feb 25;13:Article number 5.
    Link to: http://dx.doi.org/10.1186/s12979-016-0059-y
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1742-4933&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000370838100001
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84975682924
    顯示於類別:[莊淑鈞] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    PUB26918023.pdf563KbAdobe PDF536檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋