國家衛生研究院 NHRI:
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    日期题名關聯
    2019-07 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 227.
    2013-04-13 Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents FASEB Journal. 2013 Apr 13;27:lb71.
    2013-04-07 BPR000K, a novel Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
    2013-04-07 3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
    2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
    2013-04 Tylophorine induces c-Jun protein accumulation through two discrete prolonged pathways NF-kappaB/PKCdelta/JNK and PI3K/PDK1/PP2A/eEF2 to promote G1 arrest in carcinoma cells FASEB Journal. 2013 Apr;27:lb74.
    2013-04 Identification of a quinone compound inhibits human glutaminase activity and induces autophagy in carcinoma cells FASEB Journal. 2013 Apr;27:lb70.
    2013-04 Design and synthesis of Aurora kinase inhibitors as anticancer agents Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI.
    2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.
    2012-03-25 Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI.
    2011-09-23 BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo European Journal of Cancer. 2011 Sep 23;47:S127.
    2011-09 Overcoming the acquired resistance to Afatinib (BIBW2992) in HCC827, a non-small cell lung cancer cell line European Journal of Cancer. 2011 Sep;47:S129.
    2011-03-27 Design and synthesis of potent Aurora kinase inhibitors Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
    2010-08 Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models Abstracts of Papers - American Chemical Society. 2010 Aug;240:MEDI 332.
    2009-09 Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development EJC Supplements. 2009 Sep;7(2):96.
    2007-07 Anti-influenza drug discovery Drugs of the Future. 2007 Jul;32(Suppl. A):97.
    2007-04-18 Identification of novel small-molecule inhibitors of transmissible gastroenteritis virus FASEB Journal. 2007 Apr 18;21(6):LB10.
    2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141.
    2005-03 Design, synthesis and sar of indole-based PPAR agonists Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141.

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