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生技與藥物研究所
趙宇生(2002-2013)
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趙宇生(2002-2013)
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Showing items 1-19 of 19. (1 Page(s) Totally)
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Date
Title
Relation
2019-07
BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy
Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 227.
2013-04-13
Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents
FASEB Journal. 2013 Apr 13;27:lb71.
2013-04-07
BPR000K, a novel Aurora kinase inhibitor
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
2013-04-07
3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
2013-04-07
Development drug candidate targeting EGFR kinase: DBPR112
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
2013-04
Tylophorine induces c-Jun protein accumulation through two discrete prolonged pathways NF-kappaB/PKCdelta/JNK and PI3K/PDK1/PP2A/eEF2 to promote G1 arrest in carcinoma cells
FASEB Journal. 2013 Apr;27:lb74.
2013-04
Identification of a quinone compound inhibits human glutaminase activity and induces autophagy in carcinoma cells
FASEB Journal. 2013 Apr;27:lb70.
2013-04
Design and synthesis of Aurora kinase inhibitors as anticancer agents
Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI.
2012-11
BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia
European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.
2012-03-25
Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors
Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI.
2011-09-23
BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo
European Journal of Cancer. 2011 Sep 23;47:S127.
2011-09
Overcoming the acquired resistance to Afatinib (BIBW2992) in HCC827, a non-small cell lung cancer cell line
European Journal of Cancer. 2011 Sep;47:S129.
2011-03-27
Design and synthesis of potent Aurora kinase inhibitors
Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI.
2010-08
Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models
Abstracts of Papers - American Chemical Society. 2010 Aug;240:MEDI 332.
2009-09
Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development
EJC Supplements. 2009 Sep;7(2):96.
2007-07
Anti-influenza drug discovery
Drugs of the Future. 2007 Jul;32(Suppl. A):97.
2007-04-18
Identification of novel small-molecule inhibitors of transmissible gastroenteritis virus
FASEB Journal. 2007 Apr 18;21(6):LB10.
2005-03
Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141.
2005-03
Design, synthesis and sar of indole-based PPAR agonists
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141.
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