國家衛生研究院 NHRI:Item 3990099045/9709
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    題名: The role of physical activity in harm reduction among betel quid chewers from a prospective cohort of 419,378 individuals
    作者: Lo, FE;Lu, PJ;Tsai, MK;Lee, JH;Wen, C;Wen, CP;Wai, JP;Tsao, CK;Chiang, PH;Lyu, SY;Ma, KL;Chi, YC;Li, CS;Liu, CC;Wu, X
    貢獻者: Division of Health Services and Preventive Medicine
    摘要: OBJECTIVE: To assess the benefits of regular exercise in reducing harms associated with betel quid (BQ) chewing. METHODS: The study cohort, 419,378 individuals, participated in a medical screening program between 1994 and 2008, with 38,324 male and 1,495 female chewers, who consumed 5-15 quids of BQ a day. Physical activity of each individual, based on "MET-hour/week", was classified as "inactive" or "active", where activity started from a daily 15 minutes/day or more of brisk walking (>/=3.75 MET-hour/week). Hazard ratios for mortality and remaining years in life expectancy were calculated. RESULTS: Nearly one fifth (18.7%) of men, but only 0.7% of women were chewers. Chewers had a 10-fold increase in oral cancer risk; and a 2-3-fold increase in mortality from lung, esophagus and liver cancer, cardiovascular disease, and diabetes, with doubling of all-cause mortality. More than half of chewers were physically inactive (59%). Physical activity was beneficial for chewers, with a reduction of all-cause mortality by 19%. Inactive chewers had their lifespan shortened by 6.3 years, compared to non-chewers, but being active, chewers improved their health by gaining 2.5 years. The improvement, however, fell short of offsetting the harms from chewing. CONCLUSIONS: Chewers had serious health consequences, but being physically active, chewers could mitigate some of these adverse effects, and extend life expectancy by 2.5 years and reduce mortality by one fifth. Encouraging exercise, in addition to quitting chewing, remains the best advice for 1.5 million chewers in Taiwan.
    日期: 2016-04-04
    關聯: PLoS ONE. 2016 Apr 4;11(4):Article number e0152246.
    Link to: http://dx.doi.org/10.1371/journal.pone.0152246
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1932-6203&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000373592100011
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84962910464
    顯示於類別:[江博煌] 期刊論文
    [溫啟邦(2001-2010)] 期刊論文

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