國家衛生研究院 NHRI:Item 3990099045/9811
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 917155      在线人数 : 1475
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻
    主页登入上传说明关于NHRI管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/9811


    题名: Association of short-term exposure to fine particulate matter and nitrogen dioxide with acute cardiovascular effects
    作者: Wu, CF;Shen, FH;Li, YR;Tsao, TM;Tsai, MJ;Chen, CC;Hwang, JS;Hsu, SHJ;Chao, H;Chuang, KJ;Chou, CCK;Wang, YN;Ho, CC;Su, TC
    贡献者: Division of Biostatistics and Bioinformatics
    摘要: This study evaluated whether exposure to fine particulate matter (PM2.5) and nitrogen dioxide (NO2) is associated with cardiovascular effects by examining a panel of 89 healthy subjects in Taipei, Taiwan. The subjects received two health examinations approximately 8 months apart in 2013. Brachial–ankle pulse wave velocity (baPWV), a physiological indicator of arterial stiffness, and high-sensitivity C-reactive protein (hsCRP), a biomarker of vascular inflammations, were measured during each examination. Two exposure assessment methods were used for estimating the subjects' exposure to PM2.5 and NO2. The first method involved constructing daily land use regression (LUR) models according to measurements collected at ambient air quality monitoring stations. The second method required combining the LUR estimates with indoor monitoring data at the workplace of the subjects. Linear mixed models were used to examine the association between the exposure estimates and health outcomes. The results showed that a 10-μg/m3 increase in PM2.5 concentration at a 1-day lag was associated with 2.1% (95% confidence interval: 0.7%–3.6%) and 2.4% (0.8%–4.0%) increases in baPWV based on the two exposure assessment methods, whereas no significant association was observed for NO2. The significant effects of PM2.5 remained in the two-pollutant models. By contrast, NO2, but not PM2.5, was significantly associated with increased hsCRP levels (16.0%–37.3% in single-pollutant models and 26.4%–44.6% in two-pollutant models, per 10-ppb increase in NO2). In conclusion, arterial stiffness might be more sensitive to short-term PM2.5 exposure than is inflammation.
    日期: 2016-11
    關聯: Science of the Total Environment. 2016 Nov;569-570:300-305.
    Link to: http://dx.doi.org/10.1016/j.scitotenv.2016.06.084
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0048-9697&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000382269000032
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84975885818
    显示于类别:[陳主智] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    SDO0048969716312578.pdf536KbAdobe PDF487检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈