國家衛生研究院 NHRI:Items for Author
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 12145/12927 (94%)
Visitors : 925672      Online Users : 673
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
    •  Adv. Search
    Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer Goto mobile version

    Category

    Loading community tree, please wait....

    Year

    Loading year class tree, please wait....

    Items for Author "Chen, CT" 

    Return to Browse by Author

    Showing 291 items.

    Collection Date Title Relation Bitstream
    [伍素瑩] 期刊論文 2019-04-10 Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants -
    [伍素瑩] 期刊論文 2009-10 (1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases -
    [伍素瑩] 期刊論文 2009-07-23 Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity -
    [伍素瑩] 期刊論文 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities -
    [何英剛(2006-2011)] 期刊論文 2010-03 Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice -
    [余冠儀] 期刊論文 2022-05-02 Furin and TMPRSS2 resistant spike induces robust humoral and cellular immunity against SARS-CoV-2 lethal infection -
    [其他] 會議論文/會議摘要 2019-05 Assessment of photodynamic therapy (PDT) efficacy of X-ray activated nanoscintillators using F-18-HT in PET -
    [其他] 會議論文/會議摘要 2007-10 Least-square pinhole SPECT calibration using a forward projector modeling misalignment -
    [其他] 會議論文/會議摘要 2007 A system model for pinhole SPECT simulating edge penetration, detector and pinhole response and non-uniform attenuation -
    [其他] 會議論文/會議摘要 2006-10 New ray-driven system matrix for small-animal pinhole-SPECT with detector blur, geometric response and edge penetration modeling -
    [其他] 會議論文/會議摘要 2006-03 A novel model of the geometric and detector response for limited angular sampling pinhole SPECT -
    [其他] 會議論文/會議摘要 2004-10 A preliminary experimental valiadation of a new approach for pulse processing in PET -
    [其他] 會議論文/會議摘要 2004 Modular detector systems for nuclear medicine imaging -
    [其他] 期刊論文 1998-10 Characterization of p96(h2bk): Immunoreaction with an anti-Erk (extracellular-signal-regulated kinase) peptide antibody and activity in Xenopus oocytes and eggs -
    [其他] 期刊論文 2007-06 Improved accuracy of brain MRI/SPECT registration using a two-cluster SPECT normalization algorithm and a combinative similarity measure: application to the evaluation of Parkinson's disease -
    [其他] 期刊論文 2007-05 An automatic MRI/SPECT registration algorithm using image intensity and anatomical feature as matching characters: application on the evaluation of Parkinson's disease -
    [其他] 期刊論文 2023-09 Nucleus accumbens deep brain stimulation improves depressive-like behaviors through BDNF-mediated alterations in brain functional connectivity of dopaminergic pathway -
    [劉士任] 期刊論文 2022-12-02 Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodies -
    [劉柯俊] 期刊論文 2015-04 IL-1beta promotes malignant transformation and tumor aggressiveness in oral cancer -
    [劉滄梧] 期刊論文 2020-02-18 Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system -
    [吳其炘] 期刊論文 2024-01-25 Unlocking the secrets behind advanced artificial intelligence language models in deidentifying Chinese-English mixed clinical text: Development and validation study -
    [吳嘉文] 期刊論文 2023-09-07 Controlled encapsulation of gold nanoparticles into Zr-metal-organic frameworks with improved detection limitation of volatile organic compounds via surface-enhanced raman scattering -
    [周玉山(1996-2005)] 期刊論文 2004-03-19 Diverse cellular transformation capability of overexpressed genes in human hepatocellular carcinoma -
    [夏克山] 期刊論文 2022-10-03 Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention -
    [夏克山] 期刊論文 2018-02-08 Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond -
    [夏克山] 期刊論文 2015-03 Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury -
    [夏克山] 期刊論文 2012-02 Discovery of novel stem cell mobilizers that target the CXCR4 receptor -
    [夏興國] 期刊論文 2013-02 Targeted endostatin-cytosine deaminase fusion gene therapy plus 5-fluorocytosine suppresses ovarian tumor growth -
    [岳嶽] 期刊論文 2019-12 A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses -
    [岳嶽] 期刊論文 2019-08-27 A dengue virus type 2 (DENV-2) NS4B-interacting host factor, SERP1, reduces DENV-2 production by suppressing viral RNA replication -
    [岳嶽] 期刊論文 2019-03 Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A -
    [張俊彥] 期刊論文 2022-03-02 Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy -
    [張俊彥] 期刊論文 2004-07-01 BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo -
    [張文祥] 會議論文/會議摘要 2004 ALA-mediated photodynamic therapy decreases the ability of cellular invasion in CL1-5 human lung adenocarcinoma cells -
    [張文祥] 會議論文/會議摘要 2004 ALA-mediated photodynamic therapy decreases the ability of cellular invasion in CL1-5 human lung adenocarcinoma cells -
    [張文祥] 期刊論文 2009-04 ALA-PDT results in phenotypic changes and decreased cellular invasion in surviving cancer cells -
    [彭汪嘉康(1996-2007)] 期刊論文 2002-05 Phase II and pharmacokinetic study of GL331 in previously treated Chinese gastric cancer patients -
    [徐祖安] 會議論文/會議摘要 2018-12 Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer -
    [徐祖安] 會議論文/會議摘要 2018-12 Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer -
    [徐祖安] 會議論文/會議摘要 2014-03 DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study -
    [徐祖安] 期刊論文 2020-08-20 Discovery of M protease inhibitors encoded by SARS-CoV-2 -
    [徐祖安] 期刊論文 2014-01-08 Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer -
    [徐祖安] 期刊論文 2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML -
    [李秀珠] 會議論文/會議摘要 2004-09 Drug design of BPR0L075 as an anticancer agent -
    [李秀珠] 會議論文/會議摘要 2004-07 Drug design for BPR0L075 as an anticancer agent -
    [李秀珠] 期刊論文 2023-07-20 Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin -
    [李秀珠] 期刊論文 2023-01-19 The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b [Erratum:Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.] -
    [李秀珠] 期刊論文 2022-07-21 The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b -
    [李秀珠] 期刊論文 2021-08-13 Remdesivir and cyclosporine synergistically inhibit the human coronaviruses OC43 and SARS-CoV-2 -
    [李秀珠] 期刊論文 2020-12-14 Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives -
    [李秀珠] 期刊論文 2020-08 Repurposing old drugs as antiviral agents for coronaviruses -
    [李秀珠] 期刊論文 2017-07 Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors -
    [李靜琪] 期刊論文 2019-03 Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors -
    [李靜琪] 期刊論文 2018-01-01 Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 -
    [李靜琪] 期刊論文 2016-05 N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors -
    [李靜琪] 期刊論文 2012-09 Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors -
    [林名釗] 圖書 2003 Functional and molecular imaging using positron emission tomography -
    [林名釗] 會議論文/會議摘要 2007-11 A unified segmentation method for CT image segmentation with contrast agent -
    [林名釗] 會議論文/會議摘要 2005-10 A row-action image reconstruction of short time frame for microPET dynamic study -
    [林名釗] 期刊論文 2012-08 Ferritin-red fluorescent protein fusion reporter for magnetic resonance and optical imaging -
    [林名釗] 期刊論文 2010-10 RU486-inducible recombination in the salivary glands of lactoferrin promoter-driven green fluorescent Cre transgenic mice -
    [林名釗] 期刊論文 2010-04 Detection of experimentally induced pulmonary granuloma Inflammation in monocyte chemoattractant protein-1 reporter mice -
    [林名釗] 期刊論文 2009-10 Noninvasive optical imaging for tracking gene delivery and recombination in tumor -
    [林嬪嬪] 期刊論文 2012-01 Mitochondrial apoptosis and FAK signaling disruption by a novel histone deacetylase inhibitor, HTPB, in antitumor and antimetastatic mouse models -
    [梁賡義] 期刊論文 2007-08 A randomised placebo-controlled trial of a traditional chinese herbal formula in the treatment of primary dysmenorrhoea -
    [楊重熙] 會議論文/會議摘要 2016-05 In Vivo PET/CT neuroimaging of radiolabeled nanocarriers following intranasal drug delivery (INDD): Validation using Ex Vivo PET/CT, gamma counting and autoradiography -
    [涂醒哲(2003-2004)] 期刊論文 2005-03 SARS in Taiwan: an overview and lessons learned -
    [石全(2014-2017)] 會議論文/會議摘要 2020-08 BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification -
    [紀雅惠] 會議論文/會議摘要 2019-07 An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer -
    [紀雅惠] 期刊論文 2024-06-01 Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus -
    [紀雅惠] 期刊論文 2021-05-19 Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins -
    [羅履維] 圖書 2014-03 Silica nanoparticle platform -
    [羅履維] 會議論文/會議摘要 2016-10-29 Rapid measurement of fluorescence lifetimes using SIPM detection and waveform sampling -
    [羅履維] 會議論文/會議摘要 2016-05 Experimental model validation for x-ray induced luminescence imaging in tissue phantoms with europium-doped nanophosphors -
    [羅履維] 會議論文/會議摘要 2015-05 Evaluation of X-ray fuorescence emission tomography for real-time assessment of photodynamic therapy effect -
    [羅履維] 會議論文/會議摘要 2014-05 Nanoparticle-engineered probing of neural stem cells targeted therapy for glioblastoma -
    [羅履維] 會議論文/會議摘要 2014-05 Direct x-ray luminescence tomography using selective plane illumination -
    [羅履維] 會議論文/會議摘要 2013-09-08 Nanoparticle-programmed self-destructive neural stem cells for targeted glioblastoma therapy -
    [羅履維] 會議論文/會議摘要 2012-03-25 Biocompatible gold nanomaterials for optoacoustic imaging (OAI) -
    [羅履維] 期刊論文 2023-06-02 Illuminating and radiosensitizing tumors with 2DG-bound gold-based nanomedicine for targeted CT imaging and therapy -
    [羅履維] 期刊論文 2022-07-13 Multimodal magnetic resonance and photoacoustic imaging of tumor-specific enzyme-responsive hybrid nanoparticles for oxygen modulation -
    [羅履維] 期刊論文 2020-05-20 Annealing-modulated nanoscintillators for nonconventional X-ray activation of comprehensive photodynamic effects in deep cancer theranostics -
    [羅履維] 期刊論文 2019-11 A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of cre recombinase -
    [羅履維] 期刊論文 2019-04 Highly sensitive electron paramagnetic resonance nanoradicals for quantitative intracellular tumor oxymetric images -
    [羅履維] 期刊論文 2017-09 Rapid measurement of fluorescence lifetimes using SiPM detection and waveform sampling -
    [羅履維] 期刊論文 2017-08 Lectin-functionalized mesoporous silica nanoparticles for endoscopic detection of premalignant colonic lesions -
    [羅履維] 期刊論文 2016-02 Dynamic in vivo SPECT imaging of neural stem cells functionalized with radiolabeled nanoparticles for tracking of glioblastoma -
    [羅履維] 期刊論文 2014-11 Radioluminescence characterization of in situ x-ray nanodosimeters: Potential real-time monitors and modulators of external beam radiation therapy -
    [羅履維] 期刊論文 2014-08-07 Significant inhibition of tumor growth following single dose nanoparticle-enhanced photodynamic therapy -
    [羅履維] 期刊論文 2014-05-30 Enhanced plasmonic resonance energy transfer in mesoporous silica-encased gold nanorod for two-photon-activated photodynamic therapy -
    [羅履維] 期刊論文 2013-12 Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy -
    [羅履維] 期刊論文 2013-07 Theranostic applications of mesoporous silica nanoparticles and their organic/inorganic hybrids -
    [羅履維] 期刊論文 2012-12 Recent advances in nanoparticle-based föster resonance energy transfer for biosensing, molecular imaging and drug release profiling -
    [羅履維] 期刊論文 2012-04-19 Visualizing dynamics of sub-hepatic distribution of nanoparticles using intravital multiphoton fluorescence microscopy -
    [羅履維] 期刊論文 2010-08 Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics-the trio of imaging, targeting and therapy -
    [羅履維] 期刊論文 2010-07 Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles -
    [羅履維] 期刊論文 2010-01 Enhanced photoacoustic stability of gold nanorods by silica matrix confinement -
    [羅履維] 期刊論文 2009-01-23 Near-infrared mesoporous silica nanoparticles for optical imaging: Characterization and in vivo biodistribution -
    [羅秀容] 期刊論文 2012-03 R432 is a key residue for the multiple functions of Ndt80p in Candida albicans -
    [羅秀容] 期刊論文 2009-03 Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells -
    [羅秀容] 期刊論文 2006-07 Non-lethal Candida albicans cph1/cph1 efg1/efg1 transcription factor mutant establishing restricted zone of infection in a mouse model of systemic infection -
    [翁紹華] 會議論文/會議摘要 2019-07 Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216 -
    [翁紹華] 會議論文/會議摘要 2018-07 4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo -
    [翁紹華] 期刊論文 2022-12-05 Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation -
    [翁紹華] 期刊論文 2022-11 Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone -
    [翁紹華] 期刊論文 2019-04-01 The in vivo antinociceptive and mu-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone -
    [翁紹華] 期刊論文 2017-05 1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine -
    [莊聲宏(1997-2004)] 期刊論文 2004-03 Expression of cytoplasmic-domain substituted epidermal growth factor receptor inhibits tumorigenicity of EGFR-overexpressed human glioblastoma multiforme -
    [葉修華] 期刊論文 2024-10-29 DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration -
    [葉修華] 期刊論文 2024-07-17 Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia -
    [葉燈光] 專利 2014-08-15 Anticancer oral formulation -
    [葉燈光] 專利 2014-06-04 抗癌口服制剂 -
    [葉燈光] 專利 2013-06-05 Anticancer oral formulation -
    [葉燈光] 專利 2013-02-11 抗癌口服藥學組成物 -
    [葉燈光] 專利 2011-09-27 Formulations of indol-3-yl-2-oxoacetamide compounds -
    [葉燈光] 會議論文/會議摘要 2017-04 Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation -
    [葉燈光] 會議論文/會議摘要 2013-11 A development drug candidate targeting EGFR kinase for lung cancer: DBPR112 -
    [葉燈光] 期刊論文 2013-11 BPR0C305, an orally active microtubule-disrupting anticancer agent -
    [葉燈光] 期刊論文 2009-07 Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes -
    [葉燈光] 期刊論文 2008-02-28 Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet -
    [葉燈光] 期刊論文 2007-07 Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes -
    [葉燈光] 期刊論文 2006-11-25 The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes -
    [蔡世峯] 期刊論文 2010-02-09 ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway -
    [蔡世峯] 期刊論文 2009-10-09 KEAP1 E3 Ligase-Mediated Downregulation of NF-kappaB Signaling by Targeting IKKbeta -
    [蔡慧珍] 期刊論文 2016-10 BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia -
    [蔣維棠] 期刊論文 2021-01 Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease -
    [蔣維棠] 期刊論文 2019-12 Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia -
    [蔣維棠] 期刊論文 2015-07 Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations -
    [蔣維棠] 期刊論文 2013-06 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [蔣維棠] 期刊論文 2012-06-07 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [蔣維棠] 期刊論文 2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [蔣維棠] 期刊論文 2009-04-01 Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors -
    [蔣維棠] 期刊論文 2009-03-15 Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors -
    [蔣維棠] 期刊論文 2007-03-01 3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes -
    [蔣維棠] 期刊論文 2006-06-15 Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors -
    [蔣維棠] 期刊論文 2006-01-12 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV -
    [蕭子凱(2001-2004)] 專利 2009-08-21 一種定量迦瑪射線能量、高峰時間及衰減時間常數的裝置及其使用方法 -
    [蕭子凱(2001-2004)] 專利 2009-06-19 A device and method for digitizing pet radiation events -
    [蕭子凱(2001-2004)] 專利 2009-03-19 A device and method for digitizing gamma ray energy and characterizing peak time and decay time constant without the use of ADC -
    [蕭子凱(2001-2004)] 專利 2009-01-02 A device and method for digitizing gamma ray energy and characterizing peak time and decay time constant without the use Of ADC -
    [蕭子凱(2001-2004)] 專利 2008-03-11 Device and method for digitizing PET radiation events -
    [蕭子凱(2001-2004)] 專利 2007-04-03 Device and method for digitizing gamma ray energy and characterizing peak time and decay time constant without the use of ADC -
    [蕭子凱(2001-2004)] 專利 2007-02-11 一種數位化正子斷層掃瞄發射裝置及其使用方法 -
    [蕭子凱(2001-2004)] 會議論文/會議摘要 2003-10 A new approach for pulse processing in PET -
    [蕭子凱(2001-2004)] 期刊論文 2005-08 A new approach for pulse processing in positron emission tomography -
    [蕭樑基] 期刊論文 2011-07 Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model -
    [蕭金福] 圖書 2018-08-21 Design and data analysis of multiregional clinical trials (MRCTs)—Theory and practice -
    [蕭金福] 會議論文/會議摘要 2016-11-11 Assessing benefit and consistency of treatment effect under a discrete random effects model in multiregional clinical trials -
    [蕭金福] 期刊論文 2021-01 Use of a two-sided tolerance interval in the design and evaluation of biosimilarity in clinical studies -
    [蕭金福] 期刊論文 2020-10 Operational experiences in China and statistical issues on the conduct of clinical trials during the COVID-19 pandemic -
    [蕭金福] 期刊論文 2016-06 Assessing the consistency of the treatment effect under the discrete random effects model in multiregional clinical trials -
    [蕭金福] 期刊論文 2012-09 Design and evaluation of multiregional trials with heterogeneous treatment effect across regions -
    [謝興邦] 會議論文/會議摘要 2014-11 Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent -
    [謝興邦] 會議論文/會議摘要 2014-10 Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma -
    [謝興邦] 會議論文/會議摘要 2013-04-07 BPR000K, a novel Aurora kinase inhibitor -
    [謝興邦] 會議論文/會議摘要 2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 -
    [謝興邦] 會議論文/會議摘要 2013-04 Design and synthesis of Aurora kinase inhibitors as anticancer agents -
    [謝興邦] 會議論文/會議摘要 2011-03-27 Design and synthesis of potent Aurora kinase inhibitors -
    [謝興邦] 會議論文/會議摘要 2010-08 Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models -
    [謝興邦] 會議論文/會議摘要 2006-09 MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes -
    [謝興邦] 會議論文/會議摘要 2005-03 Design, synthesis and sar of indole-based PPAR agonists -
    [謝興邦] 會議論文/會議摘要 2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents -
    [謝興邦] 期刊論文 2023-02-07 Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer -
    [謝興邦] 期刊論文 2021-11-15 Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization -
    [謝興邦] 期刊論文 2021-10-14 Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model -
    [謝興邦] 期刊論文 2019-11-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer -
    [謝興邦] 期刊論文 2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation -
    [謝興邦] 期刊論文 2013-06-28 Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor -
    [謝興邦] 期刊論文 2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules -
    [謝興邦] 期刊論文 2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach -
    [謝興邦] 期刊論文 2007-02-01 Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study -
    [謝興邦] 期刊論文 2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities -
    [趙宇生(2002-2013)] 會議論文/會議摘要 2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia -
    [趙宇生(2002-2013)] 期刊論文 2012-02 Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents -
    [趙宇生(2002-2013)] 期刊論文 2011-01-13 Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes -
    [趙宇生(2002-2013)] 期刊論文 2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency -
    [趙宇生(2002-2013)] 期刊論文 2010-07 Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 -
    [郭書辰] 期刊論文 2018-10 Community-acquired bloodstream infections caused by Acinetobacter baumannii: A matched case-control study -
    [郭書辰] 期刊論文 2018-06 Risk of mortality of Catheter-Related Bloodstream Infections caused by acinetobacter species: Is early removal of the catheters associated with a better survival outcome? -
    [郭書辰] 期刊論文 2018-05 Biofilm formation is not associated with worse outcome in Acinetobacter baumannii bacteraemic pneumonia -
    [郭書辰] 期刊論文 2017-09 Multicenter study of the relationship between carbapenem MIC values and clinical outcome of patients with Acinetobacter Bacteremia -
    [郭書辰] 期刊論文 2017-09 Multicenter study of clinical features of breakthrough acinetobacter bacteremia during carbapenem therapy -
    [郭書辰] 期刊論文 2015-08 Risk factors and outcome for colistin resistant acinetobacter nosocomialis bacteraemia in patients without previous colistin exposure -
    [郭靜娟] 期刊論文 2017-12 Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells -
    [郭靜娟] 期刊論文 2015-08 Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway -
    [鄒倫] 期刊論文 2022-06-21 Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids -
    [鄒倫] 期刊論文 2022-02-15 Click chemistry and multicomponent reaction for linker diversification of zinc dipicolylamine-based drug conjugates -
    [鄒倫] 期刊論文 2021-01 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy -
    [鄒倫] 期刊論文 2019-07-11 Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates -
    [鄒倫] 期刊論文 2017-07 Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates -
    [鄒小蕙] 期刊論文 2017-09 A tolerance interval approach to assessing the biosimilarity of follow-on biologics -
    [鄒小蕙] 期刊論文 2013-11 A 12-Year ecological study of hip fracture rates among older Taiwanese adults -
    [陳主智] 期刊論文 2021-03 Projection of future temperature extremes, related mortality, and adaptation due to climate and population changes in Taiwan -
    [陳志豪] 專利 2010-05-11 咪唑啉酮化合物 -
    [陳志豪] 專利 2009-03-10 Imidazolidinone compounds -
    [陳志豪] 專利 2007-06-01 咪唑啉酮化合物 -
    [陳志豪] 專利 2006-10-31 Imidazolidinone compounds -
    [陳志豪] 期刊論文 2019-04-01 A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus -
    [陳新(2002-2015)] 期刊論文 2010-06-15 (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV -
    [陳淑貞(1998-2001)] 專利 2010-02-16 Methods of 1H-indol-3-yl-2-oxoacetamide compounds -
    [陳炯東] 專利 2010-05-11 咪唑胺化合物 -
    [陳炯東] 專利 2010-04-21 吲哚-3-基-2-氧乙醯胺衍生物之新化合物及其醫藥組合物與製備方法 -
    [陳炯東] 專利 2009-08-04 Imidazolamino compounds -
    [陳炯東] 專利 2008-12-09 Imidazolamino compounds -
    [陳炯東] 專利 2008-07-08 Use of 1H-indol-3-yl-2-oxoacetamide compounds -
    [陳炯東] 專利 2006-09-19 Imidazolamino compounds -
    [陳炯東] 專利 2005-03-01 一種用以抑制癌細胞之醫藥組合物 -
    [陳炯東] 會議論文/會議摘要 2019-07 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy -
    [陳炯東] 會議論文/會議摘要 2018-01 Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer -
    [陳炯東] 會議論文/會議摘要 2016-12 Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST -
    [陳炯東] 會議論文/會議摘要 2016-10 Multifunctional nanoparticles for oral protein drug delivery -
    [陳炯東] 會議論文/會議摘要 2016-08 Dipeptidyl peptidase-4 inhibitor LAF-237 improves glucose tolerance and expends graft beta cell mass in diabetic mice transplanted with a sufficient number of islets -
    [陳炯東] 會議論文/會議摘要 2016-02 Multifunctional nanoparticles for oral protein drug delivery -
    [陳炯東] 會議論文/會議摘要 2015-08 Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform -
    [陳炯東] 會議論文/會議摘要 2015-08 Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia -
    [陳炯東] 會議論文/會議摘要 2014-10 YYEI motif is critical to oncogenicity of 14-3-3 proteins -
    [陳炯東] 會議論文/會議摘要 2012-06 Involvement of transcriptional regulator Ndt80 in stress responses of Candida albicans -
    [陳炯東] 會議論文/會議摘要 2011-09 Effects of dipeptidyl peptidase 4 inhibition with MK-0431 on syngeneic mouse islet transplantation -
    [陳炯東] 會議論文/會議摘要 2011-05 Study of glioblastoma multiforme metastatic and invasive mechanism by polycistronic imaging probe in tumor implanted animal model -
    [陳炯東] 會議論文/會議摘要 2004 Acellular biological tissues loaded with a novel angiogenic agent (ginsenoside Rg1) as a tissue-engineering extracellular matrix -
    [陳炯東] 會議論文/會議摘要 2002-03 Sympathoinhibitory action of nociceptin in the rat spinal cord -
    [陳炯東] 期刊論文 2024-02-16 Postfermented tea extract potently alleviates glucose metabolism disorders in vitro and in vivo -
    [陳炯東] 期刊論文 2022-11-15 BPR0C261, an analogous of microtubule disrupting agent D-24851 enhances the radiosensitivity of human non-small cell lung cancer cells via p53-dependent and p53-independent pathways -
    [陳炯東] 期刊論文 2022-11-01 Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis -
    [陳炯東] 期刊論文 2022-10-13 Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate -
    [陳炯東] 期刊論文 2021-12 Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice -
    [陳炯東] 期刊論文 2021-10-01 Engineering nano- and microparticles as oral delivery vehicles to promote intestinal lymphatic drug transport -
    [陳炯東] 期刊論文 2021-08-01 DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity -
    [陳炯東] 期刊論文 2021-08 A noninvasive gut-to-brain oral drug delivery system for treating brain tumors -
    [陳炯東] 期刊論文 2020-11 Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice -
    [陳炯東] 期刊論文 2020-10-08 Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery -
    [陳炯東] 期刊論文 2020-10 A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats -
    [陳炯東] 期刊論文 2020-08 Artificial intelligence approach fighting COVID-19 with repurposing drugs -
    [陳炯東] 期刊論文 2019-09 Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1 -
    [陳炯東] 期刊論文 2019-07 Citronellol induces necroptosis of human lung cancer cells via TNF-alpha pathway and reactive oxygen species accumulation -
    [陳炯東] 期刊論文 2019-06-15 Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems -
    [陳炯東] 期刊論文 2019-03-28 Phase-changeable nanoemulsions for oral delivery of a therapeutic peptide: Toward targeting the pancreas for antidiabetic treatments using lymphatic transport -
    [陳炯東] 期刊論文 2019-01 CSC-3436 inhibits TWIST-induced epithelial-mesenchymal transition via the suppression of Twist/Bmi1/Akt pathway in head and neck squamous cell carcinoma -
    [陳炯東] 期刊論文 2019-01 CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-Beta Wnt and STAT3 signaling pathways -
    [陳炯東] 期刊論文 2018-07 An intestinal "Transformers"-like nanocarrier system for enhancing the oral bioavailability of poorly water-soluble drugs -
    [陳炯東] 期刊論文 2018-04 Effects of female sex hormones on folic acid-induced anti-angiogenesis -
    [陳炯東] 期刊論文 2018-04 PSPC1 mediates TGF-beta1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis -
    [陳炯東] 期刊論文 2017-07-07 CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-kappaB pathways -
    [陳炯東] 期刊論文 2015-09 Self-assembling bubble carriers for oral protein delivery -
    [陳炯東] 期刊論文 2014-08-04 Effects of dipeptidyl peptidase-4 inhibition with MK-0431 on syngeneic mouse islet transplantation -
    [陳炯東] 期刊論文 2014-04 Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles -
    [陳炯東] 期刊論文 2013-10 Noninvasive imaging oral absorption of insulin delivered by nanoparticles and its stimulated glucose utilization in controlling postprandial hyperglycemia during OGTT in diabetic rats -
    [陳炯東] 期刊論文 2013-10 Combination therapy via oral co-administration of insulin- and exendin-4-loaded nanoparticles to treat type 2 diabetic rats undergoing OGTT -
    [陳炯東] 期刊論文 2013-07 Andrographis paniculata extract and andrographolide modulate the hepatic drug metabolism system and plasma tolbutamide concentrations in rats -
    [陳炯東] 期刊論文 2013-06 Candida albicans ENO1 null mutants exhibit altered drug susceptibility, hyphal formation, and virulence -
    [陳炯東] 期刊論文 2013-05 H2O2 accumulation mediates differentiation capacity alteration, but not proliferative decline in senescent human fetal mesenchymal stem cells -
    [陳炯東] 期刊論文 2013-01-23 In vivo imaging of brain infarct with the novel fluorescent probe psvue 794 in a rat middle cerebral artery occlusion-reperfusion model -
    [陳炯東] 期刊論文 2013-01 Effects of pH on molecular mechanisms of chitosan–integrin interactions and resulting tight-junction disruptions -
    [陳炯東] 期刊論文 2012-09 Elucidating the signaling mechanism of an epithelial tight-junction opening induced by chitosan -
    [陳炯東] 期刊論文 2012-09 Putative tumor metastasis-associated genes in human gastric cancer -
    [陳炯東] 期刊論文 2012-09 HDAC inhibitors augmented cell migration and metastasis through induction of PKCs leading to identification of low toxicity modalities for combination cancer therapy -
    [陳炯東] 期刊論文 2012-04 Securin enhances the anti-cancer effects of 6-Methoxy-3-(3′,4′,5′-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in human colorectal cancer cells -
    [陳炯東] 期刊論文 2011-11 Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins -
    [陳炯東] 期刊論文 2011-10 Antiproliferative effects of N-heterocyclic indolyl glyoxylamide derivatives on human lung cancer cells -
    [陳炯東] 期刊論文 2011-05 Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4 -
    [陳炯東] 期刊論文 2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities -
    [陳炯東] 期刊論文 2010-12 Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening -
    [陳炯東] 期刊論文 2010-11 Self-assembled pH-sensitive nanoparticles: A platform for oral delivery of protein drugs -
    [陳炯東] 期刊論文 2010-11 Do neutrophils play a role in establishing liver abscesses and distant metastases caused by Klebsiella pneumoniae? -
    [陳炯東] 期刊論文 2010-09 Intravenous paclitaxel against metastasis of human gastric tumors of diffuse type -
    [陳炯東] 期刊論文 2010-03 Synthesis and biological activities of 2-Amino-1-arylidenamino imidazoles as orally active anticancer agents -
    [陳炯東] 期刊論文 2010-02 Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91 -
    [陳炯東] 期刊論文 2010-02 Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice -
    [陳炯東] 期刊論文 2009-04 In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery -
    [陳炯東] 期刊論文 2008-11-28 Anti-angiogenic action of 5,5-diphenyl-2-thiohydantoin-N10 (DPTH-N10) -
    [陳炯東] 期刊論文 2008-09 Human breast tumor cells express multimodal imaging reporter genes -
    [陳炯東] 期刊論文 2008-07-09 Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice -
    [陳炯東] 期刊論文 2008-06 Oral delivery of peptide drugs using nanoparticles self-assembled by poly(gamma-glutamic acid) and a chitosan derivative functionalized by trimethylation -
    [陳炯東] 期刊論文 2007-03-14 Novel nanoparticles for oral insulin delivery via the paracellular pathway -
    [陳炯東] 期刊論文 2007-03 Effects of paclitaxel and doxorubicin in histocultures of hepatocelular carcinomas -
    [陳炯東] 期刊論文 2007-01 Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery -
    [陳炯東] 期刊論文 2006-12 Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats -
    [陳炯東] 期刊論文 2006-08 Impaired phagocytosis of capsular serotypes K1 or K2 Klebsiella pneumoniae in type 2 diabetes mellitus patients with poor glycemic control -
    [陳炯東] 期刊論文 2006-03 Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer -
    [陳炯東] 期刊論文 2006-03 Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system against cultured HepG2 cells -
    [陳炯東] 期刊論文 2005-05 Loading of a novel angiogenic agent, ginsenoside Rg(1) in an acellular biological tissue for tissue regeneration -
    [陳炯東] 期刊論文 2005-04 A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration -
    [陳炯東] 期刊論文 2005-03 Preparation of nanoparticles composed of chitosan/poly-gamma-glutamic acid and evaluation of their permeability through Caco-2 cells -
    [陳炯東] 期刊論文 2004-08-10 Inhibition of human vascular endothelial cells proliferation by terbinafine -
    [陳炯東] 期刊論文 2004-04 Central pressor effects of CART peptides in anesthetized rats -
    [陳炯東] 期刊論文 2004-02 A simple quantitative method for evaluation of angiogenesis activity -
    [陳炯東] 期刊論文 2003-04-24 Synthesis and biological evaluation of N-heterocyclic indolyl glyoxylamides as orally active anticancer agents -
    [陳炯東] 期刊論文 2001-06 Time- and concentration-dependent penetration of doxorubicin in prostate tumors -
    [陳立宗] 期刊論文 2018-08-24 BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor -
    [顏婉菁] 會議論文/會議摘要 2019-10 Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117) -
    [黃秀芬] 期刊論文 2008-03 Decreased expression of UK114 is related to the differentiation status of human hepatocellular carcinoma -

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback