國家衛生研究院 NHRI:作者相關文件

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"Hung, MS"的相關文件

類別	日期	題名	關聯
[伍素瑩] 期刊論文	2020-02-10	Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors	-
[伍素瑩] 期刊論文	2016-01	Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1	-
[伍素瑩] 期刊論文	2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	-
[夏克山] 專利	2013-09-11	噻吩化合物及其醫藥組成物	-
[夏克山] 專利	2013-03-27	Thiophene compounds	-
[夏克山] 專利	2012-07-04	噻吩化合物	-
[夏克山] 專利	2011-10-01	硒吩化合物及其醫藥組成物	-
[夏克山] 專利	2011-03-21	吡唑化合物及其醫藥組成物	-
[夏克山] 專利	2010-11-16	Thiophene compounds	-
[夏克山] 專利	2010-09-28	Selenophene compounds	-
[夏克山] 期刊論文	2019-01-01	Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist	-
[夏克山] 期刊論文	2013-11-13	Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice	-
[夏克山] 期刊論文	2010-09	Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist	-
[夏克山] 期刊論文	2009-07-23	Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice	-
[夏克山] 期刊論文	2008-09-21	Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists	-
[夏克山] 期刊論文	2008-09-11	Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists	-
[夏克山] 期刊論文	2008-02-07	Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists	-
[張中和] 期刊論文	2017-11	Caveolin-1 secreted from adipose tissues and adipocytes functions as an adipogenesis enhancer	-
[施能耀] 期刊論文	2017-11-16	In silico-based identification of human alpha-enolase inhibitors to block cancer cell growth metabolically	-
[李秀珠] 期刊論文	2023-07-20	Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin	-
[洪明秀] 會議論文/會議摘要	2019-10	In vivo efficacy of cannabinoid receptor 1 antagonist, CPD1, in treating non-alcoholic fatty liver disease	-
[洪明秀] 會議論文/會議摘要	2016-12	Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy	-
[洪明秀] 會議論文/會議摘要	2014-08	A novel mechanism for acupuncture-induced analgesia: involvement of orexins and endocannabinoids	-
[洪明秀] 期刊論文	2023-01	Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists	-
[洪明秀] 期刊論文	2019-08	A structure-function approach identifies L-PGDS as a mediator responsible for glucocorticoid-induced leptin expression in adipocytes	-
[洪明秀] 期刊論文	2018-10-06	Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray	-
[洪明秀] 期刊論文	2016-07-22	Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons	-
[洪明秀] 期刊論文	2015-05	A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis	-
[洪明秀] 期刊論文	2012-07	Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors	-
[洪明秀] 期刊論文	2011-06	A new perspective of cannabinoid 1 receptor antagonists: Approaches toward peripheral CB1R blockers without crossing the blood-brain barrier	-
[洪明秀] 期刊論文	2010-10	Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities	-
[洪明秀] 期刊論文	2009-02-01	1,2,3-Triazole derivatives as new cannabinoid CB1 receptor antagonists	-
[童俊維] 期刊論文	2024-01-23	Decrypting orphan GPCR drug discovery via multitask learning	-
[翁紹華] 會議論文/會議摘要	2018-07	4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo	-
[翁紹華] 期刊論文	2022-02-05	Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design	-
[翁紹華] 期刊論文	2018-04	4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy	-
[翁紹華] 期刊論文	2016-01	Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy	-
[翁紹華] 期刊論文	2014-08	Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors	-
[莊志立] 期刊論文	2000-10	Transcriptional repression by Drosophila methyl-CpG-binding proteins	-
[蘇郁文] 期刊論文	2018-08-21	DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation	-
[許素菁] 期刊論文	2013-05	Mesenchymal stem cells tune the development of monocyte-derived dendritic cells toward a myeloid-derived suppressive phenotype through growth-regulated oncogene chemokines	-
[趙宇生(2002-2013)] 期刊論文	2011-01-13	Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes	-

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