國家衛生研究院 NHRI:Item 3990099045/10725

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Title:	Gelatin-functionalized mesoporous silica nanoparticles with sustained release properties for intracameral pharmacotherapy of glaucoma
Authors:	Liao, YT;Lee, CH;Chen, ST;Lai, JY;Wu, KCW
Contributors:	Institute of Biomedical Engineering and Nanomedicine
Abstract:	Herein, pilocarpine-loaded gelatin-covered mesoporous silica nanoparticles (denoted as p/GM) were intracamerally administrated into the anterior chamber for the reduction of intraocular pressure (IOP). The in vitro release profile shows that p/GM demostrates a high release percentage (50%) with a long-lasting release profile (36 days). The in vivo studies showed the maintenance of IOP in eye with ocular hypertension for 21 days.
Date:	2017-09
Relation:	Journal of Materials Chemistry B. 2017 Sep;5(34):7008-7013.
Link to:	http://dx.doi.org/10.1039/c7tb01217a
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2050-750X&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000408685300002
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85028612970
Appears in Collections:	[Chia-Wen Wu] Periodical Articles

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