國家衛生研究院 NHRI:Item 3990099045/10725
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    題名: Gelatin-functionalized mesoporous silica nanoparticles with sustained release properties for intracameral pharmacotherapy of glaucoma
    作者: Liao, YT;Lee, CH;Chen, ST;Lai, JY;Wu, KCW
    貢獻者: Institute of Biomedical Engineering and Nanomedicine
    摘要: Herein, pilocarpine-loaded gelatin-covered mesoporous silica nanoparticles (denoted as p/GM) were intracamerally administrated into the anterior chamber for the reduction of intraocular pressure (IOP). The in vitro release profile shows that p/GM demostrates a high release percentage (50%) with a long-lasting release profile (36 days). The in vivo studies showed the maintenance of IOP in eye with ocular hypertension for 21 days.
    日期: 2017-09
    關聯: Journal of Materials Chemistry B. 2017 Sep;5(34):7008-7013.
    Link to: http://dx.doi.org/10.1039/c7tb01217a
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2050-750X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000408685300002
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85028612970
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