國家衛生研究院 NHRI:Item 3990099045/15484
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 906227      在线人数 : 813
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/15484


    题名: Protocol for efficient human MSC chondrogenesis via Wnt antagonism instead of TGF-beta
    其它题名: Protocol for efficient human MSC chondrogenesis via Wnt antagonism instead of TGF-β
    作者: Hsieh, CC;Chang, CC;Hsu, PJ;Chen, L;Yen, BL
    贡献者: Institute of Cellular and Systems Medicine
    摘要: To better implement mesenchymal stem cell (MSC)-based therapy toward cartilage diseases, a more efficient and less off-target chondrogenesis protocol is needed. Here, we present a protocol to induce human MSC chondrogenesis via Wnt antagonism. We describe steps for pellet formation, Wnt antagonism-based chondrogenic induction, and refreshing the differentiation medium. We detail procedures for characterizing MSC chondrogenesis. By using Wnt antagonism instead of conventional transforming growth factor β-based induction, this protocol avoids the potential for induction of chondrocyte hypertrophy/osteogenesis or other lineages. For complete details on the use and execution of this protocol, please refer to Hsieh et al.
    日期: 2023-12-15
    關聯: STAR Protocols. 2023 Dec 15;4(4):Article number 102728.
    Link to: http://dx.doi.org/10.1016/j.xpro.2023.102728
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85176938954
    显示于类别:[顏伶汝] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    SCP85176938954.pdf2879KbAdobe PDF152检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈