In this study, a novel method for the alkoxylation of ketones has been developed, employing sulfuric acid and N-heterocyclic carbene boranes (NHC−boranes). The ketones are reduced using NHC−borane (diMe-Imd-BH3) and subsequently alkoxylate with sulfuric acid in alcohol solvents. Due to the stability of NHC−borane in the presence of both moisture and air, this reaction emerges as an effective and accessible approach for organic synthesis.
Date:
2024-09-27
Relation:
Asian Journal of Organic Chemistry. 2024 Sep 27;Article in Press.
