國家衛生研究院 NHRI:Item 3990099045/1758
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    题名: A unified multipoint linkage analysis of qualitative and quantitative traits for sib-pairs
    作者: Chang, IS;Chen, MY;Hsiao, CF;Hsiung, CA
    贡献者: Division of Biostatistics and Bioinformatics;National Institute of Cancer Research
    摘要: By introducing functions of the phenotypes of a sib-pair as weight functions in the study of IBD processes, we present a unified non-parametric approach to linkage analysis of qualitative and quantitative traits in sib-pairs based on IBD data obtained from a set of polymorphic markers. With the introduction of weight functions and an appropriate conditional expectation of IBD processes, these statistical methods should be more efficient in the detection of genetic factors for complex diseases. These methods will be also useful in planning genetic studies. Large sample properties of these methods axe demonstrated.
    关键词: Statistics & Probability
    日期: 2002-01
    關聯: Statistica Sinica. 2002 Jan;12(1):297-309.
    Link to: http://www3.stat.sinica.edu.tw/statistica/j12n1/j12n115/j12n115.htm
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1017-0405&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000174372800016
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0036376970
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