國家衛生研究院 NHRI:Item 3990099045/1979
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    題名: A 5-year study of the seroepidemiology of Klebsiella pneumoniae: High prevalence of capsular serotype K1 in Taiwan and implication for vaccine efficacy
    作者: Fung, CP;Hu, BS;Chang, FY;Lee, SC;Kuo, BIT;Ho, MT;Siu, LK;Liu, CY
    貢獻者: Division of Clinical Research
    摘要: Seroepidemiology of Klebsiella pneumoniae was determined for 1000 nonrepetitive K, pneumoniae isolates collected by a medical center in Taiwan during 1993-1997, Of these, 630 isolates (63%) were from community-acquired infections; the rest were from hospital-acquired infections. The isolates were serotyped according to capsular antigen by countercurrent immunoelectrophoresis. About 77% were typeable. Serotypes K1 and K2 accounted for 21.7% and 9.3% of the isolates, respectively, followed by K57 (5.1%), K54 (4.2%), K21 (3.3%), and K16 (3%), The frequency of serotype K1 among bacteremic isolates (30.8%) far exceeded that reported by other investigators worldwide. Molecular typing of random K1 isolates by pulsed-field gel electrophoresis revealed several different pulsotypes, suggesting a nonclonal spread. This study indicates that a Klebsiella vaccine developed in Europe is not optimal for use in Taiwan because it does not contain the most predominant serotypes-K1, K54, and K57.
    關鍵詞: Infectious Diseases
    日期: 2000-06
    關聯: Journal of Infectious Diseases. 2000 Jun;181(6):2075-2079.
    Link to: http://dx.doi.org/10.1086/315488
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0022-1899&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000087923900033
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034100093
    顯示於類別:[蕭樑基] 期刊論文
    [何曼德(1997-2002)] 期刊論文

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