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日期	題名	關聯
2014-09	Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents	Bioorganic and Medicinal Chemistry. 2014 Sep;22(17):4917-4923.
2014-08	Two new acidic diterpenoids from the heartwood of Pinus massoniana LAMB	Helvetica Chimica Acta. 2014 Aug;97(8):1146-1151.
2013-11-21	治療癌症的醫藥組成物	I415852/2013-11-21
2013-09	MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1α mrna through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR [Erratum: Molecular Cancer Therapeutics. 2013 Jul;12(7):1202-1212.]	Molecular Cancer Therapeutics. 2013 Sep;12(9):1919.
2013-09	Furanylazaindoles: Potent anticancer agents in vitro and in vivo	Journal of Medicinal Chemistry. 2013 Sep;56(20):8008-8018.
2013-07-19	Surface alpha-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target	PLoS ONE. 2013 Jul 19;8(7):Article number e69354.
2013-07	MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1 alpha mRNA through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR	Molecular Cancer Therapeutics. 2013 Jul;12(7):1202-1212.
2013-06	Aconitamide, a novel alkaloid from the roots of aconitum carmichaeli	Natural Product Communications. 2013 Jun;8(6):827-828.
2013-06	Two new lignans from the wood of cunninghamia konishii	Natural Product Communications. 2013 Jun;8(6):805-806.
2013-03-15	Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from antrodia camphorata on the inflammatory mediator expression in mice	Journal of Agricultural and Food Chemistry. 2013 Mar 15;61(21):5064-5071.
2013-03-12	A novel synthetic microtubule inhibitor, MPT0B214 exhibits antitumor activity in human tumor cells through mitochondria-dependent intrinsic pathway	PLoS ONE. 2013 Mar 12;8(3):Article number e58953.
2012-12	Arginine deprivation as a new treatment strategy for head and neck cancer	Oral Oncology. 2012 Dec;48(12):1227-1235.
2012-12	An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold	Journal of the Chinese Chemical Society. 2012 Dec;59(12):1548-1554.
2012-12	Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines	Organic and Biomolecular Chemistry. 2012 Dec;10(48):9593-9600.
2012-11	Blockage of Nrf2/AKR1C axis enhanced therapeutic efficacy of oxaliplatin in oxaliplatin resistant gastric cancer cells	European Journal of Cancer. 2012 Nov;48(Suppl. 6):48.
2012-10	Adlay (薏苡 yi yi; “soft-shelled job’s tears”, the seeds of Coix lachryma-jobi L. var. ma-yuen Stapf) is a potential cancer chemopreventive agent toward multistage carcinogenesis processes	Journal of Traditional and Complementary Medicine. 2012 Oct;2(4):267-275.
2012-04	Targeting cathepsin S induces tumor cell autophagy via the EGFR-Erk signaling pathway	Cancer Letters. 2012 Apr;317(1):89-98.
2012-03	4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling	Free Radical Biology and Medicine. 2012 Mar;52(6):1054-1066.
2011-12-22	5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2	Journal of Medicinal Chemistry. 2011 Dec 22;54(24):8517-8525.
2011-12-15	Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors	Free Radical Biology and Medicine. 2011 Dec 15;51(12):2195-2209.
2011-11-15	Coumarin compounds and their use for treating cancer	US8058427B2/2011-11-15
2011-10	Novel terpenoids from calocedrus macrolepis var. formosana	Chemistry and Biodiversity. 2011 Oct;8(10):1901-1907.
2011-09	Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents	European Journal of Medicinal Chemistry. 2011 Sep;46(9):3623-3629.
2011-09	DNA repair enzyme, O6-methylguanine DNa methyltransferase, modulates therapeutic efficacy of platinum drugs with radiation and its clinical significance	European Journal of Cancer. 2011 Sep;47:S132.
2011-06	Antimutagenic constituents of adlay ( Coix lachryma-jobi L. var. ma-yuen Stapf) with potential cancer chemopreventive activity	Journal of Agricultural and Food Chemistry. 2011 Jun;59(12):6444-6452.
2011-06	Cytotoxic steroidal saponins from agave sisalana	Planta Medica. 2011 Jun;77(9):929-933.
2011-04-28	Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents	Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080.
2011-04	Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation	Organic and Biomolecular Chemistry. 2011 Apr;9(9):3154-3157.
2011-04	Activation of Akt/FoxO axis confers resistance to cisplatin in human nasopharyngeal carcinomas	Cancer Research. 2011 Apr;71:Abstract number 1701.
2011-04	Activation of NRF2/ABCC1 axis confers resistance to topoisomerase II poisons in human oral malignancies	Cancer Research. 2011 Apr;71:Abstract number 1528.
2011-04	MPT0B098, a novel microtubule inhibitor, displays potent anti-angiogenic activity via destabilizing hypoxia-inducible factor-1alpha mRNA	Cancer Research. 2011 Apr;71(Suppl. 8):Meeting Abstract 4461.
2011-04	Targeting cathepsin S induces tumor cell autophagy via the EGFR-ERK signaling pathway	Cancer Research. 2011 Apr;71(Suppl. 8):Meeting Abstract 2864.
2011-03-07	Synthesis and biological evaluation of 4-aroyl-6,7,8-trimethoxyquinolines as a novel class of anticancer agents	Molecules. 2011 Mar 7;16(3):2274-2284.
2011-03-07	2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors	ChemMedChem. 2011 Mar 7;6(3):450-456.
2011-01-26	Labdanecaryophyllic acid, a novel cytotoxic C35 terpenoid from Calocedrus macrolepis var. formosana	Tetrahedron Letters. 2011 Jan 26;52(4):515-517.
2010-10	Combined modalities of resistance in a cisplatin-driven human betel-associated oral squamous cell carcinoma	Annals of Oncology. 2010 Oct;21(Suppl. 8):52.
2010-08	Synthesis and biological evaluation of 7-arylindoline-1-benzenesulfonamides as a novel class of potent anticancer agents	MedChemComm. 2010 Aug;1(2):152-155.
2010-06-18	Cytotoxic C35 terpenoid cryptotrione from the bark of cryptomeria japonica	Organic Letters. 2010 Jun;12(12):2786-2789.
2010-06	Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis	Journal of Medicinal Chemistry. 2010 Jun;53(11):4545-4549.
2010-05	Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells	Biochemical Pharmacology. 2010 May;79(9):1261-1271.
2010-04	Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis	Oral Oncology. 2010 Apr;46(4):255-262.
2010-03-11	5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors	Journal of Medicinal Chemistry. 2010 Mar 11;53(5):2309-2313.
2009-11-01	Effects of drying and extrusion on colour, chemical composition, antioxidant activities and mitogenic response of spleen lymphocytes of sweet potatoes	Food Chemistry. 2009 Nov 1;117(1):114-121.
2009-09	Synergistic augmentation of arsenic trioxide-induced cytotoxicity by BCNU through reactive oxygen species-related autophagic pathway in human solid tumors	EJC Supplements. 2009 Sep;7(3):16.
2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945.
2009-07-23	Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity	Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233.
2009-07-03	Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers	Molecular Cancer. 2009 Jul 3;8:Article number 43.
2009-05	HQO-0601, an amide-containg 3, 4-dihydroquinolinone derivative, against human hematologic malignancies through inhibition of mammalian target of repamycin signaling pathway	Cancer Research. 2009 May;69:Abstract number LB-51.
2009-04-17	Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents	ChemMedChem. 2009 Apr 17;4(4):588-593.
2008-12-25	Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents	Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167.

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