鄰近類別 會議論文/會議摘要 [4/5] 專利 [0/36] 類別統計 近3年內發表的文件:2(5.00%) 含全文筆數:39(97.50%) 文件下載次數統計 下載大於0次:39(100.00%) 下載大於100次:37(94.87%) 檔案下載總次數:29385(92.78%) 最後更新時間: 2025-02-26 13:05 上傳排行 資料載入中..... 下載排行 資料載入中..... 最近上傳 Advancing precision therapy for col... Development of potent and selective... Xanthine derivatives reveal an allo... DBPR108, a novel dipeptidyl peptida... Potent and orally active purine-bas... Identification of a multitargeted t... Identification of novel anti-liver ... Discovery of Conformational Control... BPR1J373, a novel multitargeted kin... Pyrazolylamine derivatives reveal t...

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日期	題名	關聯
2025-01	Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models	Pharmacological Research. 2025 Jan;211:Article number 107556.
2024-11-26	Development of potent and selective inhibitors of methylenetetrahydrofolate dehydrogenase 2 for targeting acute myeloid leukemia: Sar, structural insights, and biological characterization	Journal of Medicinal Chemistry. 2024 Nov 26;67(23):21106-21125.
2021-08-12	Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2)	Journal of Medicinal Chemistry. 2021 Aug 12;64(15):11288-11301.
2021-08-01	DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity	Life Sciences. 2021 Aug 1;278:Article number 119574.
2021-01	Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease	European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938.
2019-12	Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia	Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150.
2019-05-28	Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform	Cancers. 2019 May 28;11(6):Article number 739.
2019-04-10	Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants	Journal of Medicinal Chemistry. 2019 Apr 10;62(8):3940-3957.
2018-08-24	BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor	Cancer Science. 2018 Nov;109(11):3591-3601.
2016-10	BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia	Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.

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