Collection 專利 [0/23] 期刊論文 [37/38] 會議論文/會議摘要 [4/5] Siblings 伍素瑩 [52/65] 其他 [58/60] 夏克山 [76/98] 岳嶽 [29/32] 張仲明 [7/9] 張俊彥 [18/18] 張竣評 [21/26] 徐祖安 [170/215] 李秀珠 [75/105] 李靜琪 [23/24] 林書玉 [19/20] 洪明秀 [31/40] 潘秀玲(2009-2013) [16/17] 王文傑 [13/15] 王鴻俊 [7/7] 石全(2014-2017) [35/39] 童俊維 [23/23] 紀雅惠 [21/25] 翁紹華 [22/24] 莊宏 [1/1] 葉修華 [24/25] 葉燈光 [133/152] 謝興邦 [171/231] 趙宇生(2002-2013) [120/212] 郭靜娟 [49/55] 鄒倫 [28/29] 陳志豪 [31/52] 陳新(2002-2015) [53/67] 陳炯東 [180/212] 顏婉菁 [6/7] 許明珠(1997-2001) [3/10] 陳淑貞(1998-2001) [3/11] 陳華鍵(1997-2001) [9/9] Community Statistics 近3年內發表的文件:0(0.00%) 含全文筆數:41(62.12%) 文件下載次數統計 下載大於0次:41(100.00%) 下載大於100次:41(100.00%) 檔案下載總次數:30800(0.57%) 最後更新時間: 2024-11-28 13:34 Top Upload Loading... Top Download Loading... Recent Submissions Xanthine derivatives reveal an allo... DBPR108, a novel dipeptidyl peptida... Potent and orally active purine-bas... Identification of a multitargeted t... Use of integrated genomic analyses ... Identification of novel anti-liver ... Discovery of Conformational Control... BPR1J373, a novel multitargeted kin... Novel cKIT kinase inhibitor, BPRCKJ... Pyrazolylamine derivatives reveal t...

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Showing items 1-25 of 66. (3 Page(s) Totally) 1 2 3 > >> View [10|25|50] records per page

Date	Title	Relation
2021-08-12	Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2)	Journal of Medicinal Chemistry. 2021 Aug 12;64(15):11288-11301.
2021-08-01	DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity	Life Sciences. 2021 Aug 1;278:Article number 119574.
2021-01	Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease	European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938.
2019-12	Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia	Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150.
2019-07	Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216	Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 4626.
2019-05-28	Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform	Cancers. 2019 May 28;11(6):Article number 739.
2019-04-10	Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants	Journal of Medicinal Chemistry. 2019 Apr 10;62(8):3940-3957.
2018-08-24	BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor	Cancer Science. 2018 Nov;109(11):3591-3601.
2016-12	Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST	Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
2016-10	BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia	Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.
2016-04-12	Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK)	Journal of Medicinal Chemistry. 2016 Apr 12;59(8):3906-3919.
2015-07	Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations	European Journal of Medicinal Chemistry. 2015 Jul;100:151-161.
2014-08-01	Pyrrolidine derivatives	特許第5,586,484號/2014-08-01
2014-05-12	Pyrrolidine derivatives	J001349/2014-05-12
2014-05-08	Pyrrolidine derivatives	AU2009222198/2014-05-08
2014-04-25	Pyrrolidine derivatives	HK1149261/2014-04-25
2014-04-21	作為蛋白質激酶抑制劑之吡唑化合物及噻唑化合物、其醫藥組成物及用途	I434834/2014-04-21
2014-02-19	Pyrrolidine derivatives	EP2252582/2014-02-19
2014-02	Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation	PLoS ONE. 2014 Feb 13;9(2):Article number e88772.
2014-01-08	Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer	PLoS ONE. 2014 Jan 8;9(1):Article number e83160.
2014-01	A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease	Antimicrobial Agents and Chemotherapy. 2014 Jan;58(1):110-119.
2013-12-18	吡咯烷化合物	ZL200980107941.2/2013-12-18
2013-09-27	Pyrrolidine derivatives	RU2494094C2/2013-09-27
2013-06-28	Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor	Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260.
2013-06	Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867.

Showing items 1-25 of 66. (3 Page(s) Totally) 1 2 3 > >> View [10|25|50] records per page