國家衛生研究院 NHRI:Item 3990099045/3398
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    题名: Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells
    作者: Yang, YL;Wang, CW;Chen, CT;Wang, MH;Hsiao, CF;Lo, HJ
    贡献者: Division of Clinical Research;Division of Biostatistics and Bioinformatics;Division of Biotechnology and Pharmaceutical Research
    摘要: Although Candida albicans cph1/cph1 efg1/efg1 mutant cells are not lethal to mice, they proliferated in infected mice instead of simply being cleared by the host immune system. Here, we have shown that the cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by the lethal wild-type Candida albicans cells. Our results further indicate that a second dose of the cph1/cph1 efg1/efg1 mutant did not boost the degree of protection.
    日期: 2009-03
    關聯: Mycological Research. 2009 Mar;113(3):388-390.
    Link to: http://dx.doi.org/10.1016/j.mycres.2008.11.016
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000264693700011
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=60849102762
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