國家衛生研究院 NHRI:
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    显示项目1-43 / 43. (共1页)
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    日期题名關聯
    2024-09-20 The mitochondrial stress signaling tunes immunity from a view of systemic tumor microenvironment and ecosystem iScience. 2024 Sep 20;27(9):Article number 110710.
    2024-09-18 Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells Experimental and Molecular Medicine. 2024 Sep 18;56:2065-2081.
    2024-06-17 Tumor promoting effect of PDLIM2 downregulation involves mitochondrial ROS, oncometabolite accumulations and HIF-1alpha activation Journal of Experimental and Clinical Cancer Research. 2024 Jun 17;43:Article number 169.
    2023-10 Metastasis and immunosuppression promoted by mtDNA and PD-L1 in extracellular vesicles are reversed by WGP beta-glucan in oral squamous cell carcinoma Cancer Science. 2023 Oct;114(10):3857-3872.
    2023-03-16 Mitochondrial Lon-induced mitophagy benefits hypoxic resistance via Ca2+-dependent FUNDC1 phosphorylation at the ER-mitochondria interface Cell Death and Disease. 2023 Mar 16;14(3):Article number 199.
    2023-02 A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment Cancer Immunology Immunotherapy. 2023 Feb;72(2):351-369.
    2022-09-26 Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend? Journal of Biomedical Science. 2022 Sep 26;29:Article number 74.
    2022-09 Beta-glucan therapy converts the inhibition of myeloid-derived suppressor cells in oral cancer patients Oral Diseases. 2022 Sep;28(6):1484-149.
    2022-05 Sharpening up tumor microenvironment to enhance the efficacy of immune checkpoint blockade on head and neck cancer using a CpG-oligodeoxynucleotide Cancer Immunology, Immunotherapy. 2022 May;71(5):1115-1128.
    2022-03-16 Lon upregulation contributes to cisplatin resistance by triggering NCLX-mediated mitochondrial Ca2+ release in cancer cells Cell Death and Disease. 2022 Mar 16;13(3):Article number 241.
    2021-03 Insulin-like growth factor binding protein 3 promotes radiosensitivity of oral squamous cell carcinoma cells via positive feedback on NF-kappa B/IL-6/ROS signaling Journal of Experimental and Clinical Cancer Research. 2021 Mar;40:Article number 95.
    2021-01-26 Bifunctional mechanisms of autophagy and apoptosis regulations in melanoma from Bacillus subtilis natto fermentation extract Food and Chemical Toxicology. 2021 Jan 26;150:Article number 112020.
    2021-01-15 Unlocking the mystery of the therapeutic effects of Chinese medicine on cancer Frontiers in Pharmacology. 2021 Jan 15;11:Article number 601785.
    2020-12-11 Establishment of an immunocompetent metastasis rat model with hepatocyte cancer stem cells Cancers. 2020 Dec 11;12(12):Article number 3721.
    2020-12 Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1-mediated immunoescape via STING-IFN signaling and extracellular vesicles Journal for ImmunoTherapy of Cancer. 2020 Dec;8(2):Article number e001372.
    2020-04 A time-saving-modified Giemsa stain is a better diagnostic method of Helicobacter pylori infection compared with the rapid urease test Journal of Clinical Laboratory Analysis. 2020 Apr;34(4):Article number e23110.
    2020-01-24 Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis Cancer Letters. 2020 Jan 24;474:138-150.
    2019-07-11 USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation[Erratum: Oncogene. 2018 Dec 6;37(49):6327-6340.] Oncogene. 2019 Jul 11;38(28):5742-5743.
    2019-05 TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response PLoS Genetics. 2019 May;15(5):Article number e1007947.
    2018-12-06 USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation Oncogene. 2018 Dec 6;37(49):6327-6340.
    2018-11 AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells Journal of Biomedical Science. 2018 Nov;25:Article number 80.
    2018-10 Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach EBioMedicine. 2018 Oct;36:241-251.
    2018-06-13 Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity Cell Death and Disease. 2018 Jun 13;9:Article number 697.
    2017-12 Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer Scientific Reports. 2017 Dec;7:Article number 17024.
    2016-08-02 Warfarin and coumarin-like Murraya paniculata extract down-regulate EpCAM-mediated cell adhesion: Individual components versus mixture for studying botanical metastatic chemopreventives Scientific Reports. 2016 Aug 2;6:Article number 30549.
    2016-05 Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma Molecular Carcinogenesis. 2016 May;55(5):499-513.
    2016-01 The novel VEGF121-VEGF165 fusion attenuates angiogenesis and drug resistance via targeting VEGFR2-HIF-1alpha-VEGF165/Lon signaling through PI3K-AKT-mTOR pathway Current Cancer Drug Targets. 2016 Jan;6(3):275-286.
    2015-10 Mitigation of cerebellar neuropathy in globoid cell leukodystrophy mice by AAV-mediated gene therapy Gene. 2015 Oct;187(1):81-90.
    2015-09 Curcumin Inhibits Invasiveness and epithelial-mesenchymal transition in oral squamous cell carcinoma through reducing matrix metalloproteinase 2, 9 and modulating p53-E-cadherin pathway Integrative Cancer Therapies. 2015 Sep;14(5):484-490.
    2015-07 Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia Mitochondrion. 2015 Jul;23:7-16.
    2015-02 Mitochondrial Lon regulates apoptosis through the association with Hsp60-mtHsp70 complex Cell Death and Disease. 2015 Feb;6:Article number e1642.
    2014-08 Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma International Journal of Cancer. 2014 Aug;135(4):809–819.
    2014-08 Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition (EMT) in zebrafish Oncotarget. 2014 Aug;5(15):6300-6311.
    2014-02 Structural basis for DNA-mediated allosteric regulation facilitated by the AAA(+) module of Lon protease Acta Crystallographica. Section D, Biological Crystallography. 2014 Feb;70(Pt 2):218-230.
    2013-10 Expression of E-cadherin, Twist, and p53 and their prognostic value in patients with oral squamous cell carcinoma Journal of Cancer Research and Clinical Oncology. 2013 Oct;139(10):1735-1744.
    2013-09 Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents Cancer Letters. 2013 Sep;337(2):218-225.
    2013-06 Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species Cell Death and Disease. 2013 Jun;4:Article number e681.
    2012-11-08 Spermine attenuates the action of the DNA intercalator, actinomycin D, on DNA binding and the inhibition of transcription and DNA replication PLoS ONE. 2012 Nov 8;7(11):Article number e47101.
    2012-08 Prodigiosin down-regulates SKP2 to induce p27KIP1 stabilization and antiproliferation in human lung adenocarcinoma cells British Journal of Pharmacology. 2012 Aug;166(7):2095-2108.
    2012-07 Inhibition of ATR-dependent signaling by protoapigenone and its derivative sensitizes cancer cells to interstrand cross-link-generating agents in vitro and in vivo Molecular Cancer Therapeutics. 2012 Jul;11(7):1443-1453.
    2012-01-20 Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint Journal of Biological Chemistry. 2012 Jan 20;287(4):2531-2543.
    2010-12 Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints Cancer Science. 2010 Dec;101(12):2612-2620.
    2010-06 Antioxidants from the leaves of cinnamomum kotoense Natural Product Communications. 2010 Jun;5(6):911-912.

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