國家衛生研究院 NHRI:Item 3990099045/4776
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4776


    Title: Effects of nuisance parameters on the family-based linkage tests under general disease models
    Other Titles: Proceedings on the International Symposium on Parallel Architectures, Algorithms and Networks, I-SPAN
    Authors: Chen, KC
    Contributors: Division of Molecular and Genomic Medicine
    Abstract: Family-based linkage tests are methods for detection of the genetic basis of a disease. For the case-parent triad data, it is known that tests of linkage interfere with the association parameter under recessive disease models. The purpose of the paper is to discuss the effects of nuisance parameters on the family-based linkage tests under general models. It is shown that the linkage tests do not only interfere with the association parameter, but also with the gene substitution effect in general models.
    Date: 2004-05
    Relation: Proceedings on the International Symposium on Parallel Architectures, Algorithms and Networks, I-SPAN. 2004 May:614-618.
    Link to: https://dx.doi.org/10.1109/ISPAN.2004.1300546
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000222086800099
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=3543134873
    Appears in Collections:[Others] Conference Papers/Meeting Abstract

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