國家衛生研究院 NHRI:Item 3990099045/4776
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    題名: Effects of nuisance parameters on the family-based linkage tests under general disease models
    其他題名: Proceedings on the International Symposium on Parallel Architectures, Algorithms and Networks, I-SPAN
    作者: Chen, KC
    貢獻者: Division of Molecular and Genomic Medicine
    摘要: Family-based linkage tests are methods for detection of the genetic basis of a disease. For the case-parent triad data, it is known that tests of linkage interfere with the association parameter under recessive disease models. The purpose of the paper is to discuss the effects of nuisance parameters on the family-based linkage tests under general models. It is shown that the linkage tests do not only interfere with the association parameter, but also with the gene substitution effect in general models.
    日期: 2004-05
    關聯: Proceedings on the International Symposium on Parallel Architectures, Algorithms and Networks, I-SPAN. 2004 May:614-618.
    Link to: https://dx.doi.org/10.1109/ISPAN.2004.1300546
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000222086800099
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=3543134873
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