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顯示項目26-50 / 144. (共6頁) << < 1 2 3 4 5 6 > >> 每頁顯示[10|25|50]項目

日期	題名	關聯
2018-08-24	BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor	Cancer Science. 2018 Nov;109(11):3591-3601.
2018-01-23	Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity	Journal of Biomedical Science. 2018 Jan 23;25:Article number 6.
2017-09-26	Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains	Scientific Reports. 2017 Sep 26;7:Article number 12336.
2017-07	Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates	Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892.
2017-01	A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide	Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247.
2016-12	Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer	Oncotarget. 2016 Dec;7(52):85917-85928.
2016-12	Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Oncotarget. 2016 Dec;7(52):86239-86256.
2016-11-29	Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design	European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
2016-10	BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia	Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.
2016-09	Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy	Journal of Biological Chemistry. 2016 Sep;291(37):19299-19311.
2016-07-28	Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors	European Journal of Medicinal Chemistry. 2016 Jul 28;123:397-406.
2016-05-19	Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses	OncoTargets and Therapy. 2016 May 19;9:2961-2973.
2016-02-26	Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development	Scientific Reports. 2016 Feb 26;6:Article number 21662.
2016-01-01	Bispecific antibody conjugated manganese-based magnetic engineered iron oxide for imaging of HER2/neu- and EGFR-expressing tumors	Theranostics. 2016 Jan 1;6(1):118-130.
2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819.
2015-07	Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations	European Journal of Medicinal Chemistry. 2015 Jul;100:151-161.
2015-06-29	Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification	Scientific Reports. 2015 Jun 29;5:Article number 11702.
2015-06-16	Anchor-based classification and type-C inhibitors for tyrosine kinases	Scientific Reports. 2015 Jun 16;5:Article number 10938.
2015-01-02	KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity	Journal of Biomedical Science. 2015 Jan 2;22:Article number 2.
2015-01	Identification of ligand efficient, fragment-like hits from an HTS library: Structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity	Journal of Computer-Aided Molecular Design. 2015 Jan;29(1):89-100.
2014-12	BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71	Antiviral Research. 2014 Dec;112:18-25.
2014-11-20	The combination effects of LiCl and the active leflunomide metabolite, A771726, on viral-induced interleukin 6 production and EV-A71 replication	PLoS ONE. 2014 Nov 20;9(11):Article number e111331.
2014-11	Reticulon 3 interacts with NS4B of the hepatitis C virus and negatively regulates viral replication by disrupting NS4B self-interaction	Cellular Microbiology. 2014 Nov;16(11):1603-1618.
2014-08	Ligand efficiency based approach for efficient virtual screening of compound libraries	European Journal of Medicinal Chemistry. 2014 Aug;83:226-235.
2014-05	Facile identification of dual FLT3-Aurora A inhibitors: A computer-guided drug design approach	ChemMedChem. 2014 May;9(5):953-961.

顯示項目26-50 / 144. (共6頁) << < 1 2 3 4 5 6 > >> 每頁顯示[10|25|50]項目