邻近类别 會議論文/會議摘要 [27/39] 專利 [0/32] 类别统计 近3年内发表的文件:8(5.56%) 含全文笔数:143(99.31%) 文件下载次数统计 下载大于0次:143(100.00%) 下载大于100次:141(98.60%) 全文下载总次数:87248(84.49%) 最后更新时间: 2024-12-01 00:21 上传排行 数据加载中..... 下载排行 数据加载中..... 最近上传 Development of a humanized antibody... Reducing brain Abeta burden amelior... Development of furanopyrimidine-bas... Targeting the phosphatidylserine-im... Synthesis and evaluation of small m... Extracellular HSP90alpha induces My... The beneficial effects of combining... Acyl-coenzyme a synthetase long-cha... Colloidal assemblies composed of po... The effects of Abeta1-42 binding to...

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显示项目1-25 / 144. (共6页) 1 2 3 4 5 6 > >> 每页显示[10|25|50]项目

日期	题名	關聯
2024-07-04	Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells	Cells. 2024 Jul 04;13(13):Article number 1146.
2024-04	Reducing brain Abeta burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice	Biomedicine and Pharmacotherapy. 2024 Apr;173:Article number 116404.
2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2022-10-13	Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate	Journal of Medicinal Chemistry. 2022 Oct 13;65(19):12802-12824.
2022-06-21	Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids	Pharmaceutics. 2022 Jun 21;14(7):Article number 1316.
2022-01-18	Acyl-coenzyme a synthetase long-chain family member 4 is involved in viral replication organelle formation and facilitates virus replication via ferroptosis	mBio. 2022 Jan 18;13(1):Article number e0271721.
2022-01-11	Extracellular HSP90alpha induces MyD88-IRAK complex-associated IKKalpha/Beta−NF-KappaB/IRF3 and JAK2/TYK2−STAT-3 signaling in macrophages for tumor-promoting M2-polarization	Cells. 2022 Jan 11;11(2):Article number 229.
2022-01-05	The beneficial effects of combining anti-Abeta antibody NP106 and curcumin analog TML-6 on the treatment of Alzheimer’s disease in APP/PS1 mice	International Journal of Molecular Sciences. 2022 Jan 5;23(1):Article number 556.
2021-07-30	The effects of Abeta1-42 binding to the SARS-CoV-2 spike protein S1 subunit and angiotensin-converting enzyme 2	International Journal of Molecular Sciences. 2021 Jul 30;22(15):Article number 8226.
2021-07-16	Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens	Nanomaterials. 2021 Jul 16;11(7):Article number 1844.
2021-01	Effect of a neuropilin-1-derived virus receptor trap on enterovirus A71 infection in vitro	Antimicrobial Agents and Chemotherapy. 2021 Jan;65(1):Article number e00695-20.
2020-12	Engineering a novel IgG-like bispecific antibody against enterovirus A71	Biochemistry and Biophysics Reports. 2020 Dec;24:Article number 100860.
2020-08-20	Discovery of M protease inhibitors encoded by SARS-CoV-2	Antimicrobial Agents and Chemotherapy. 2020 Aug 20;64(9):e00872-20.
2020-08	Artificial intelligence approach fighting COVID-19 with repurposing drugs	Biomedical Journal. 2020 Aug;43(4):355-362.
2020-08	Repurposing old drugs as antiviral agents for coronaviruses	Biomedical Journal. 2020 Aug;43(4):368-374.
2020-06-02	Zika virus NS3 protease pharmacophore anchor model and drug discovery	Scientific Reports. 2020 Jun 2;10:Article number 8929.
2020-05	Antiviral activity of llama-inspired single domain antibody against Enterovirus A71	Antimicrobial Agents and Chemotherapy. 2020 May;64(5):Article number e01922-19.
2020-05	Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors	Bioorganic Chemistry. 2020 May;98:Article number 103689.
2020-04	BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine	Neuropharmacology. 2020 Apr;166:Article number 107678.
2019-11-27	Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123.
2019-07-11	Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates	Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062.
2019-05-28	Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform	Cancers. 2019 May 28;11(6):Article number 739.
2019-04-01	A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus	European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
2019-02-20	Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice	Scientific Reports. 2019 Feb 20;9:Article number 2405.
2018-10	Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach	EBioMedicine. 2018 Oct;36:241-251.

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