| 2018-08-24 |
BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor |
Cancer Science. 2018 Nov;109(11):3591-3601. |
 |
| 2018-01-23 |
Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity |
Journal of Biomedical Science. 2018 Jan 23;25:Article number 6. |
|
| 2017-09-26 |
Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains |
Scientific Reports. 2017 Sep 26;7:Article number 12336. |
|
| 2017-07 |
Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates |
Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892. |
|
| 2017-01 |
A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide |
Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247. |
|
| 2016-12 |
Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer |
Oncotarget. 2016 Dec;7(52):85917-85928. |
|
| 2016-12 |
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
Oncotarget. 2016 Dec;7(52):86239-86256. |
|
| 2016-11-29 |
Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design |
European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199. |
|
| 2016-10 |
BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia |
Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333. |
|
| 2016-09 |
Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy |
Journal of Biological Chemistry. 2016 Sep;291(37):19299-19311. |
|
| 2016-07-28 |
Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors |
European Journal of Medicinal Chemistry. 2016 Jul 28;123:397-406. |
|
| 2016-05-19 |
Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses |
OncoTargets and Therapy. 2016 May 19;9:2961-2973. |
|
| 2016-02-26 |
Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development |
Scientific Reports. 2016 Feb 26;6:Article number 21662. |
|
| 2016-01-01 |
Bispecific antibody conjugated manganese-based magnetic engineered iron oxide for imaging of HER2/neu- and EGFR-expressing tumors |
Theranostics. 2016 Jan 1;6(1):118-130. |
|
| 2015-10 |
Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening |
Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819. |
|
| 2015-07 |
Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations |
European Journal of Medicinal Chemistry. 2015 Jul;100:151-161. |
|
| 2015-06-29 |
Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification |
Scientific Reports. 2015 Jun 29;5:Article number 11702. |
|
| 2015-06-16 |
Anchor-based classification and type-C inhibitors for tyrosine kinases |
Scientific Reports. 2015 Jun 16;5:Article number 10938. |
|
| 2015-01-02 |
KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity |
Journal of Biomedical Science. 2015 Jan 2;22:Article number 2. |
|
| 2015-01 |
Identification of ligand efficient, fragment-like hits from an HTS library: Structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity |
Journal of Computer-Aided Molecular Design. 2015 Jan;29(1):89-100. |
|
| 2014-12 |
BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71 |
Antiviral Research. 2014 Dec;112:18-25. |
|
| 2014-11-20 |
The combination effects of LiCl and the active leflunomide metabolite, A771726, on viral-induced interleukin 6 production and EV-A71 replication |
PLoS ONE. 2014 Nov 20;9(11):Article number e111331. |
|
| 2014-11 |
Reticulon 3 interacts with NS4B of the hepatitis C virus and negatively regulates viral replication by disrupting NS4B self-interaction |
Cellular Microbiology. 2014 Nov;16(11):1603-1618. |
|
| 2014-08 |
Ligand efficiency based approach for efficient virtual screening of compound libraries |
European Journal of Medicinal Chemistry. 2014 Aug;83:226-235. |
|
| 2014-05 |
Facile identification of dual FLT3-Aurora A inhibitors: A computer-guided drug design approach |
ChemMedChem. 2014 May;9(5):953-961. |
|
