| 2012-06-15 |
Targeted Casp8AP2 methylation increases drug resistance in mesenchymal stem cells and cancer cells |
Biochemical and Biophysical Research Communications. 2012 Jun 15;422(4):578-585. |
 |
| 2012-04 |
Targeting cathepsin S induces tumor cell autophagy via the EGFR-Erk signaling pathway |
Cancer Letters. 2012 Apr;317(1):89-98. |
|
| 2012-03 |
Modulation of chemotactic and pro-inflammatory activities of endothelial progenitor cells by hepatocellular carcinoma |
Cellular Signalling. 2012 Mar;24(3):779-793. |
|
| 2012-01 |
Differences in the frequencies of K-ras c12-13 genotypes by gender and pathologic phenotypes in colorectal tumors measured using the allele discrimination method |
Environmental and Molecular Mutagenesis. 2012 Jan;53(1):22-31. |
|
| 2011-12-22 |
5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2 |
Journal of Medicinal Chemistry. 2011 Dec 22;54(24):8517-8525. |
|
| 2011-12-15 |
Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors |
Free Radical Biology and Medicine. 2011 Dec 15;51(12):2195-2209. |
|
| 2011-12 |
Induction chemotherapy with gemcitabine, oxaliplatin, and 5-Fluorouracil/Leucovorin followed by concomitant chemoradiotherapy in patients with locally advanced pancreatic cancer: A Taiwan cooperative oncology group phase II study |
International Journal of Radiation Oncology, Biology, Physics. 2011 Dec;81(5):e749-e757. |
|
| 2011-11-15 |
Novel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo |
Clinical Cancer Research. 2011 Nov 15;17(22):7116-7126. |
|
| 2011-10-01 |
Enhancement of non-homologous end joining DNA repair capacity confers cancer cells resistance to the novel selenophene compound, D-501036 |
Cancer Letters. 2011 Oct 1;309(1):110-118. |
|
| 2011-10 |
Novel terpenoids from calocedrus macrolepis var. formosana |
Chemistry and Biodiversity. 2011 Oct;8(10):1901-1907. |
|
| 2011-09 |
Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents |
European Journal of Medicinal Chemistry. 2011 Sep;46(9):3623-3629. |
|
| 2011-08 |
Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer |
Oncogene. 2011 Aug;30(33):3570-3584. |
|
| 2011-08 |
BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells |
PLoS ONE. 2011 Aug;6(8):Article number e23485. |
|
| 2011-06 |
Antimutagenic constituents of adlay ( Coix lachryma-jobi L. var. ma-yuen Stapf) with potential cancer chemopreventive activity |
Journal of Agricultural and Food Chemistry. 2011 Jun;59(12):6444-6452. |
|
| 2011-06 |
Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10) |
Expert Opinion on Therapeutic Patents. 2011 Jun;21(6):857-884. |
|
| 2011-04-28 |
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents |
Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080. |
|
| 2011-04 |
Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation |
Organic and Biomolecular Chemistry. 2011 Apr;9(9):3154-3157. |
|
| 2011-03-07 |
Synthesis and biological evaluation of 4-aroyl-6,7,8-trimethoxyquinolines as a novel class of anticancer agents |
Molecules. 2011 Mar 7;16(3):2274-2284. |
|
| 2011-03-07 |
2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors |
ChemMedChem. 2011 Mar 7;6(3):450-456. |
|
| 2011-01-26 |
Labdanecaryophyllic acid, a novel cytotoxic C35 terpenoid from Calocedrus macrolepis var. formosana |
Tetrahedron Letters. 2011 Jan 26;52(4):515-517. |
|
| 2011-01 |
BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities |
Cancer Science. 2011 Jan;102(1):182-191. |
|
| 2011-01 |
Investigations of survivin: the past, present and future |
Frontiers in Bioscience. 2011 Jan;16:952-961. |
|
| 2010-12 |
Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells |
Molecular Cancer. 2010 Dec;9:Article number 309 |
|
| 2010-10 |
MBP-1 is efficiently encoded by an alternative transcript of the ENO1 gene but post-translationally regulated by proteasome-dependent protein turnover |
FEBS Journal. 2010 Oct;277(20):4308-4231. |
|
| 2010-09 |
Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes |
PLoS ONE. 2010 Sep;5(9):Article number e12564. |
|
| 2010-08 |
Synthesis and biological evaluation of 7-arylindoline-1-benzenesulfonamides as a novel class of potent anticancer agents |
MedChemComm. 2010 Aug;1(2):152-155. |
|
| 2010-06-18 |
Cytotoxic C35 terpenoid cryptotrione from the bark of cryptomeria japonica |
Organic Letters. 2010 Jun;12(12):2786-2789. |
|
| 2010-06 |
Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis |
Journal of Medicinal Chemistry. 2010 Jun;53(11):4545-4549. |
|
| 2010-05 |
Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells |
Biochemical Pharmacology. 2010 May;79(9):1261-1271. |
|
| 2010-05 |
Recent advances in anti-survivin treatments for cancer |
Current Medicinal Chemistry. 2010 May;17(15):1509-1515. |
|
| 2010-04-15 |
Targeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells |
Molecular Cancer. 2010 Apr 15;9:Article number 77. |
|
| 2010-04 |
Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis |
Oral Oncology. 2010 Apr;46(4):255-262. |
|
| 2010-03-11 |
5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors |
Journal of Medicinal Chemistry. 2010 Mar 11;53(5):2309-2313. |
|
| 2010-03 |
Paclitaxel and carboplatin-induced complete remission in peritoneal carcinomatosis of unknown origin: A report of two cases and review of the literature |
Tumori. 2010 Mar-Apr;96(2):336-339. |
|
| 2010-02 |
Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91 |
Pharmacological Research. 2010 Feb;61(2):108-115. |
|
| 2009-12 |
Alpha-fetoprotein response in advanced hepatocellular carcinoma receiving cytostatic agent |
Journal of Clinical Oncology. 2009 Dec;27(36):e271. |
|
| 2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach |
Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945. |
|
| 2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity |
Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233. |
|
| 2009-07-03 |
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers |
Molecular Cancer. 2009 Jul 3;8:Article number 43. |
|
| 2009-04-17 |
Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents |
ChemMedChem. 2009 Apr 17;4(4):588-593. |
|
| 2009-04 |
Aurora kinase inhibitors in preclinical and clinical testing |
Expert Opinion on Investigational Drugs. 2009 Apr;18(4):379-398. |
|
| 2009-04 |
Increasing incidence of intrahepatic cholangiocarcinoma and its relationship to chronic viral hepatitis |
Journal of the National Comprehensive Cancer Network. 2009 Apr;7(4):423-427. |
|
| 2009-03 |
Advances in Aurora kinase inhibitor patents |
Expert Opinion on Therapeutic Patents. 2009 Mar;19(3):321-356. |
|
| 2008-12-25 |
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents |
Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167. |
|
| 2008-10-28 |
Human DNA polymerase eta activity and translocation is regulated by phosphorylation |
Proceedings of the National Academy of Sciences of the United States of America. 2008 Oct 28;105(43):16578-16583. |
|
| 2008-10 |
Modern staging and utility of PET imaging in esophageal cancer management |
Journal of the National Comprehensive Cancer Network. 2008 Oct;6(9):862-869. |
|
| 2008-08 |
Transcriptional repression of O-6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N '-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells |
Molecular Pharmacology. 2008 Aug;74(2):517-526. |
|
| 2008-07-24 |
Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors |
Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355. |
|
| 2008-02 |
A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells |
Anti-Cancer Drugs. 2008 Feb;19(2):151-158. |
|
| 2007-11-15 |
Tamoxifen accelerates proteasomal degradation of O-6-methylguanine DNA methyltransferase in human cancer cells |
International Journal of Cancer. 2007 Nov;121(10):2293-2300. |
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