國家衛生研究院 NHRI:Item 3990099045/5738
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 915185      線上人數 : 1352
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/5738


    題名: The quantitative detection of aripiprazole and its main metabolite by using capillary-electrophoresis
    作者: Tsai, CJ;Yu, YH;Chiu, HJ;Loh, EW;Wang, JT;Chan, CH;Lan, TH
    貢獻者: Division of Mental Health and Addiction Medicine
    摘要: Background:We aimed to establish a feasible and reliable method to measure the level of aripiprazole and its main metabolite, dehydroaripiprazole, using a capillary-electrophoresis (CE) machine. Methods:Two blood samples were obtained from psychiatric patients hospitalized in Yu-Li Hospital who had been treated with aripiprazole for more than 4 weeks, at least 10 mg/d. Conditions for voltage, temperature and buffer concentration was optimized on a CE machine. Results:The most optimal conditions for CE were 80 mM 2–3% DMSO-phosphate as a buffer under pH = 3.0, 15 KV, 20°C and a detection wavelength of 214 nm. The linear ranges of aripiprazole and dehydroaripiprazole concentration were from 0.5 to 50 ng/mL. Conclusion:CE method is a feasible method to measure aripiprazole level with relatively low price compared with other analytical techniques for clinical use.
    日期: 2011-06
    關聯: Journal of the Chinese Medical Association. 2011 Jun;74(6):267-271.
    Link to: http://dx.doi.org/10.1016/j.jcma.2011.04.006
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1726-4901&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000292342400006
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79957446835
    顯示於類別:[羅爾維(2004-2012)] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    SCP79955711845.pdf249KbAdobe PDF921檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋