國家衛生研究院 NHRI:Item 3990099045/6174

NHRI > Institute of Biotechnology and Pharmaceutical Research > Kak-Shan Shia > Periodical Articles > Item 3990099045/6174

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/6174

Title:	Discovery of novel stem cell mobilizers that target the CXCR4 receptor
Authors:	Wu, CH;Chang, CP;Song, JS;Jan, JJ;Chou, MC;Wu, SH;Yeh, KC;Wong, YC;Hsieh, CJ;Chen, CT;Kao, TT;Wu, SY;Yeh, CF;Tseng, CT;Chao, YS;Shia, KS
Contributors:	Institute of Biotechnology and Pharmaceutical Research
Abstract:	Going mobile: Based on screening hit 1, a novel class of polyamine compounds, as represented by compound 8, were identified as potent and selective CXCR4 antagonists. CXCR4-targeted molecules, as demonstrated by the marketed AMD3100 and 8, are able to mobilize stem cells from bone marrow effectively and are expected to have broad utility in cell therapy and regenerative medicine.
Date:	2012-02
Relation:	ChemMedChem. 2012 Feb;7(2):209-212.
Link to:	http://dx.doi.org/10.1002/cmdc.201100525
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1860-7179&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000299630400003
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84863081475
Appears in Collections:	[Kak-Shan Shia] Periodical Articles [Su-Ying Wu] Periodical Articles [Chiung-Tong Chen] Periodical Articles [Yu-Sheng Chao(2002-2013)] Periodical Articles [Chun-Ping Chang] Periodical Articles

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